Journal List > Investig Clin Urol > v.57(4) > 1088068

Yeo and Kim: The authors reply: Korean clinical practice guideline for benign prostatic hyperplasia
To the editor:
The level of recommendation is an indicator of the grading of recommendation degree in taking into account overall such as the balance of profit and loss and cost-effectiveness or cost-benefit aspects after evaluating the level of evidence. In consideration of clinical usability, it eventually have been proposed to the strength of recommendation, a higher level of evidence generally becomes higher level of recommendation. But it is possible to give higher level of recommendation even if low level of evidence depending on panel consensus in the clinical practice guideline (CPG) [123].
If we had to use the recommendation levels of more than 3 steps, we could show a more definite recommendation level in our CPG. But there were often the "strong" recommendations because of simplifying 2-stage recommendation levels. Also in part of the diagnosis we should face the situation not enough higher level literatures. It should be understood that we could not reduce the level of recommendation to "weak" for low evidence level in the cases were clinically deserved. For example 2015 European Association of Urology guideline gave a higher level of recommendation through a panel consensus even if low level of evidence in the diagnosis part of the male lower urinary tract symptoms guideline [4].
It is well known way to be recognized internationally that guideline was made with the method of GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group. We will have a plan to try a change the level of recommendation to be recognized internationally in the Korean Urological Association guidelines.

Notes

CONFLICTS OF INTEREST The authors have nothing to disclose.

References

1. Guyatt GH, Oxman AD, Kunz R, Falck-Ytter Y, Vist GE, Liberati A, et al. Going from evidence to recommendations. BMJ. 2008; 336:1049–1051.
2. The GRADE working group. GRADE handbook [Internet]. London: The Cochrane Collaboration;2013. cited 2016 Jun 3. Available from: http://training.cochrane.org/ko/resource/grade-handbook.
3. Seo KH, Lee SH, Shin ES, Lim SM, Jang JE, Jung YM, et al. Trend analysis of grading systems for level of evidence and strength of recommendation. J Korean Med Assoc. 2011; 54:758–768.
4. Gratzke C, Bachmann A, Descazeaud A, Drake MJ, Madersbacher S, Mamoulakis C, et al. EAU guidelines on the assessment of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol. 2015; 67:1099–1109.
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