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Lee, Kang, Kim, Jeong, Kim, Kim, Lee, Bae, and Kang: Multiple Solitary Plasmacytomas Arising in the Posterior Mediastinum and Sternum: A Case Report
Chest Radiology

Journal of the Korean Society of Radiology 2016; 74(3): 199-203.

Published online: 29 February 2016

DOI: https://doi.org/10.3348/jksr.2016.74.3.199

Multiple Solitary Plasmacytomas Arising in the Posterior Mediastinum and Sternum: A Case Report

Subin Lee, MD1, Mi-Jin Kang, MD1, Jae Hyung Kim, MD1, Myeong Ja Jeong, MD1, Soung Hee Kim, MD1, Ji-Young Kim, MD1, Ji Hae Lee, MD1, Kyung Eun Bae, MD1, Tae Kyung Kang, MD2

1Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

2Department of Emergency Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

Corresponding author: Mi-Jin Kang, MD. Department of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul 01757, Korea. Tel. 82-2-950-1187, Fax. 82-2-950-1220, s2621@paik.ac.kr

Received 3 June 2015       Revised 18 August 2015       Accepted 29 August 2015

Copyright © 2016 The Korean Society of Radiology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Multiple solitary plasmacytoma is very rare disease, which occurs in multiple sites of soft tissue, bone or both without multiple myeloma. Almost 80–90% of extramedullary plasmacytomas develop in the head and neck area. Involvement of the mediastinum is extremely rare. A few cases of mediastinal plasmacytoma have been reported, and to the best of our knowledge, there is only one previous report of multiple plasmacytomas involving the posterior mediastinum. Herein, we describe an unusual case of multiple solitary plasmacytomas in a 67-year-old male involving the posterior mediastinum and sternum without evidence of bone marrow involvement.

Keywords: Multiple Solitary Plasmacytoma, Plasmacytoma, Plasma Cell Tumor, Posterior Mediastinum

Figures and Tables

Fig. 1

Plain radiograph and chest CT scan in 67-year-old man with multiple solitary plasmacytomas.

Plain radiograph (A) shows thickening of the bilateral paravertebral stripe (black arrows) and bilateral pleural effusion (white arrows). Pre-contrast (B) and post-contrast chest CT (C) images show a heterogeneously enhanced soft tissue mass (white arrows) in the posterior mediastinum at T10 level. Mass encases the abdominal aorta and intercostal arteries (black arrowheads) without definite evidence of invasion. Esophagus (white arrowhead) is replaced anteriorly. Delayed phase of abdominal CT (D) image shows gradual and heterogenous enhancement. Post-contrast CT (E) image shows a round shape osteolytic lesion with sclerotic rim (arrow) in the manubrium of the sternum.
jksr-74-199-g001
Fig. 2

PET-CT scan in 67-year-old man with multiple solitary plasmacytomas. PET-CT scan shows 18F-FDG hot uptake in the posterior mediastinum (maxSUV 4.6), T10 vertebral body (maxSUV 3.9) and sternal mass (maxSUV 4.4). It also shows hot uptake in the T8 (maxSUV 5.7) and L3 (maxSUV 3.8) vertebrae (not shown).

FDG = fluorodeoxyglucose, maxSUV = maximum standardized uptake value, PET-CT = positron emission tomography-computed tomography
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