Journal List > J Korean Soc Radiol > v.70(5) > 1087396

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Suh, Lee, Kim, Park, and Kim: The Combination of Neuroendocrine Tumor and Mucinous Neoplasm of the Appendix: A Case Report
Abdominal Radiology

Journal of the Korean Society of Radiology 2014; 70(5): 355-358.

Published online: 8 May 2014

DOI: https://doi.org/10.3348/jksr.2014.70.5.355

The Combination of Neuroendocrine Tumor and Mucinous Neoplasm of the Appendix: A Case Report

Hie Bum Suh, MD1, Nam Kyung Lee, MD1, Suk Kim, MD1, Won Young Park, MD2, Jae Hun Kim, MD3

1Department of Radiology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

2Department of Pathology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

3Department of Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.

Corresponding author: Nam Kyung Lee, MD. Department of Radiology, Pusan National University Hospital, Pusan National University School of Medicine, 179 Gudeok-ro, Seo-gu, Busan 602-739, Korea. Tel. 82-51-240-7354, Fax. 82-51-244-7534, leenk77@hanmail.net

Received 9 January 2014       Accepted 15 March 2014

Copyright © 2014 The Korean Society of Radiology

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary neoplasm of the appendix is an uncommon pathology, representing 0.5-1% of all appendix specimens. Especially, simultaneous occurrence of two tumors of the appendix was rarely documented. We report a case of the concomitant neuroendocrine tumor and the mucinous neoplasm of the appendix on abdominal computed tomography, in a 62-year-old female who came for a check-up.

Keywords: Appendix, Neuroendocrine Tumor, Mucocele, Computed Tomography

Figures and Tables

Fig. 1
A 62-year-old woman who presented with a neuroendocrine tumor and mucinous cystadenoma in the appendix.
A. Axial contrast-enhanced CT shows a 1.1 cm sized well-defined enhancing mass (arrow) in the orifice of the appendix.
B. Axial contrast-enhanced CT (caudal than A) shows a cystic mass (arrow) with peripheral calcification contiguous with base of cecum.
C. Coronal-reformatted contrast-enhanced CT shows the rupture of the cystic mass (arrow) and periappendiceal fluid collection. Scalloping of the liver margin (arrowheads) is noted.
D. Photograph of the cut gross specimens reveals cystic dilation of the appendix (arrows) and a subserosal mass (arrowheads) at the orifice of the appendix.
E. Photomicrograph (original magnification, × 20 hematoxylin-eosin stain) of cystic dilation in the appendix shows replaced neoplastic mucinous epithelium with single layers, sometimes with papillary tufting. Nuclei are small and regular with low grade dysplasia.
F. Photomicrograph (original magnification, × 20 hematoxylin-eosin stain) of the mass in the orifice of the appendix shows neoplastic neuroendocrine cells arranged in rounded solid nests. Tumor cells show moderate pleomorphism with occasionally seen hyperchromatic and large nuclei.
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