Journal List > J Korean Soc Radiol > v.66(5) > 1087116

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Lee, Cho, Shin, Ohm, and Kang: Three-Phase CT Findings of Combined Hepatocellular and Cholangiocarcinomas
Original Article
Abdominal Radiology
Journal of the Korean Society of Radiology

Journal of the Korean Society of Radiology 2012; 66(5): 443-450.

Published online: 3 May 2012

DOI: https://doi.org/10.0000/jksr.2012.66.5.443

Three-Phase CT Findings of Combined Hepatocellular and Cholangiocarcinomas

Jeong Eun Lee, MD1, June-Sik Cho, MD1, Kyung-Sook Shin, MD1, Joon Young Ohm, MD2, Dae-Young Kang, MD3

1Department of Radiology, Chungnam National University Hospital, Daejeon, Korea.

2Department of Radiology, Bucheon St. Mary's Hospital, Bucheon, Korea.

3Department of Pathology, Chungnam National University Hospital, Daejeon, Korea.

Corresponding author: June-Sik Cho, MD. Department of Radiology, Chungnam National University Hospital, 282 Munhwa-ro, Jung-gu, Daejeon 301-721, Korea. Tel. 82-42-280-7333, Fax. 82-42-253-0061, jscho@cnu.ac.kr

Received 3 October 2011       Accepted 6 March 2012

Copyright © 2012 The Korean Society of Radiology

Abstract

Purpose

To evaluate three-phase CT findings of combined hepatocellular and cholangiocarcinomas (cHCC-CCs), with an emphasis on the enhancement pattern.

Materials and Methods

We retrospectively analyzed CT findings in 11 patients with histopathologically proven 11 cHCC-CCs. Three-phase CT findings of cHCC-CCs during the arterial phase (AP), portal venous phase (PVP), and equilibrium phase (EP) were evaluated, based on the morphologic and enhancement pattern.

Results

Two (18%) of all the tumors showed arterial enhancement during the AP and delayed washout during the PVP and EP. Three tumors (27%) showed no arterial enhancement and delayed washout or delayed enhancement during the same phases. The remaining six tumors (55%) showed both arterial enhancement and delayed enhancement during the same phases.

Conclusion

Three-phase CT findings of cHCC-CCs were found to be variable, according to the histologic proportion of HCC or CC components. However, cHCC-CC could be considered when a tumor shows both arterial enhancement and delayed enhancement at three-phase CT.

Keywords: Liver, Neoplasms, Liver, CT, Hepatocellular Carcinoma, Cholangiocarcinoma

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