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Lee, Jin, Park, Han, Lee, Kwon, and Kim: Variation of the Degree of Coronary Artery Stenosis during the Cardiac Cycle: Influence of Heart Rate or Calcium Score on Coronary CT Angiography
Original Article
Cardiovascular Radiology
Journal of the Korean Society of Radiology

Journal of the Korean Society of Radiology 2012; 66(3): 221-228.

Published online: 21 March 2012

DOI: https://doi.org/10.0000/jksr.2012.66.3.221

Variation of the Degree of Coronary Artery Stenosis during the Cardiac Cycle: Influence of Heart Rate or Calcium Score on Coronary CT Angiography

Hyun Kyung Lee, MD1, Gong Yong Jin, MD1, Jae Keun Park, MD1, Young Min Han, MD1, Young Sun Lee, MD1, Keun Sang Kwon, MD2, Song Soo Kim, MD3

1Department of Radiology, Chonbuk National University Hospital and Medical School, Research Institute of Clinical Medicine, Institute of Cardiovascular Research, Jeonju, Korea.

2Department of Preventive Medicine, Chonbuk National University Hospital and Medical School, Research Institute of Clinical Medicine, Institute of Cardiovascular Research, Jeonju, Korea.

3Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.

Corresponding author: Gong Yong Jin, MD. Department of Diagnostic Radiology, Chonbuk National University Hospital and Medical School, 20 Geonji-ro, Deokjin-gu, Jeonju 561-712, Korea. Tel. 82-63-250-2307, Fax. 82-63-272-0481, gyjin@chonbuk.ac.kr

Received 28 September 2011       Accepted 10 January 2012

Copyright © 2012 The Korean Society of Radiology

Abstract

Purpose

To assess the stenotic coronary artery diameter in systole and end-diastole by coronary CT angiography and to evaluate the change in diameter according to heart rate and calcium score.

Materials and Methods

Twenty-seven patients with coronary artery stenosis that underwent a coronary CT angiography and invasive coronary angiography were enrolled in the study. We assessed the percentage of diameter change in the stenotic coronary artery between the systolic and end-diastolic phase and evaluated its relationship with heart rate or Agatston score using a linear regression analysis.

Results

The mean difference in the change of vessel diameter was 12.9% for a heart rate of 50-59 beats/min (bpm), 11.3% for 60-69 bpm, 10% for 70-79 bpm, 20% for 80-89 bpm, 13% for 90-99 bpm, and 6.7% for 100-109 bpm, none of which were statistically significant (p = 0.760). For the Agatston score, the mean difference in the change of vessel diameter was 8.3% for a score < 100, 12.4% for 100-400, and 20% for > 400. The relationship between the change in diameter and Agatston score was statistically significant (p = 0.004).

Conclusion

The data suggest that a change in diameter of the stenotic coronary artery in systole and end-diastole might be affected by the Agatston score.

Keywords: Diagnosis, Computer-Assisted, Dual Source Computed Tomography, Coronary Angiography, Coronary Stenosis

References

1. Johnson TR, Nikolaou K, Wintersperger BJ, Leber AW, von Ziegler F, Rist C, et al. Dual-source CT cardiac imaging: initial experience. Eur Radiol. 2006. 16:1409–1415.
2. Scheffel H, Alkadhi H, Plass A, Vachenauer R, Desbiolles L, Gaemperli O, et al. Accuracy of dual-source CT coronary angiography: first experience in a high pre-test probability population without heart rate control. Eur Radiol. 2006. 16:2739–2747.
3. Achenbach S, Ropers D, Kuettner A, Flohr T, Ohnesorge B, Bruder H, et al. Contrast-enhanced coronary artery visualization by dual-source computed tomography--initial experience. Eur J Radiol. 2006. 57:331–335.
4. Zhang LJ, Wu SY, Wang J, Lu Y, Zhang ZL, Jiang SS, et al. Diagnostic accuracy of dual-source CT coronary angiography: the effect of average heart rate, heart rate variability, and calcium score in a clinical perspective. Acta Radiol. 2010. 51:727–740.
5. Weustink AC, Neefjes LA, Kyrzopoulos S, van Straten M, Neoh Eu R, Meijboom WB, et al. Impact of heart rate frequency and variability on radiation exposure, image quality, and diagnostic performance in dual-source spiral CT coronary angiography. Radiology. 2009. 253:672–680.
6. Leschka S, Husmann L, Desbiolles LM, Gaemperli O, Schepis T, Koepfli P, et al. Optimal image reconstruction intervals for non-invasive coronary angiography with 64-slice CT. Eur Radiol. 2006. 16:1964–1972.
7. Seifarth H, Wienbeck S, Püsken M, Juergens KU, Maintz D, Vahlhaus C, et al. Optimal systolic and diastolic reconstruction windows for coronary CT angiography using dual-source CT. AJR Am J Roentgenol. 2007. 189:1317–1323.
8. Matt D, Scheffel H, Leschka S, Flohr TG, Marincek B, Kaufmann PA, et al. Dual-source CT coronary angiography: image quality, mean heart rate, and heart rate variability. AJR Am J Roentgenol. 2007. 189:567–573.
9. Austen WG, Edwards JE, Frye RL, Gensini GG, Gott VL, Griffith LS, et al. A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation. 1975. 51:5–40.
10. Meng L, Cui L, Cheng Y, Wu X, Tang Y, Wang Y, et al. Effect of heart rate and coronary calcification on the diagnostic accuracy of the dual-source CT coronary angiography in patients with suspected coronary artery disease. Korean J Radiol. 2009. 10:347–354.
11. Chung CS, Karamanoglu M, Kovács SJ. Duration of diastole and its phases as a function of heart rate during supine bicycle exercise. Am J Physiol Heart Circ Physiol. 2004. 287:H2003–H2008.
12. Herzog C, Zwerner PL, Doll JR, Nielsen CD, Nguyen SA, Savino G, et al. Significant coronary artery stenosis: comparison on per-patient and per-vessel or per-segment basis at 64-section CT angiography. Radiology. 2007. 244:112–120.
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