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Abstract
Peripheral primitive neuroectodermal tumors (peripheral PNETs) are very rare and highly aggressive soft-tissue malignancies originating from the neural crest. To the best of our knowledge, only a few cases of peripheral PNETs of the stomach have been reported in the literature. We report a case of large peripheral primitive neuroectodermal tumor of the stomach with MDCT findings in a 22-year-old man presenting epigastric pain and vomiting.
Figures and Tables
Fig. 1
Peripheral primitive neuroectodermal tumor of the stomach in a 22-year-old man.
A. Photograph from conventional gastroscopy shows a large submucosal mass arising from the gastric body and antrum.
B, C. Coronal and sagittal MPR images of contrast-enhanced MDCT shows a large lobulated solid mass arising from the gastric body and antrum with endogastric and exogastric growth and relatively smooth outer border. Note two regional lymph nodes metastases (arrows) in the perigastric space.
D. Photograph of gross specimen shows a large lobulated mass (12×9 cm in size) with invasion to the whole layer of gastric wall and extensive perigastric fat tissue.
E. Photomicrograph shows small round cells with invasion to the submucosal layer of gastric wall and extensive necrosis. Note distinctive lobular architecture with fibrous septa (H & E staining, ×40).
F. Photomicrograph of an immunohistochemistry for detecting MIC2 protein (CD99) shows intense tumor cells membranous immunoreactivity (×400).
References
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