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Kim, Ahn, Joung, and Park: Lipid Profiles and Prevalence of Dyslipidemia in Korean Adolescents
Original Article
Endocrinology and Metabolism

Endocrinology and Metabolism 2012; 27(3): 208-216.

Published online: 19 September 2012

DOI: https://doi.org/10.3803/EnM.2012.27.3.208

Lipid Profiles and Prevalence of Dyslipidemia in Korean Adolescents

Shin Hye Kim, Byung Chul Ahn1, Hyojee Joung2, Mi Jung Park

Department of Pediatrics, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

1Department of Pediatrics, Yeungnam University School of Economics and Finance, Gyeongsan, Korea.

2Department of Public Health Nutrition, Seoul National University School of Public Health, Seoul, Korea.

Corresponding authors: Mi Jung Park. Department of Pediatrics, Inje University Sanggye Paik Hospital, Inje University College of Medicine, 1342 Dongil-ro, Nowon-gu, Seoul 139-707, Korea. Tel: +82-2-950-1130, Fax: +82-2-951-1246, pmj@paik.ac.kr, Hyojee Joung. Department of Public Health Nutrition, Seoul National University School of Public Health, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea. Tel: +82-2-740-8865, Fax: +82-2-883-2832, hjjoung@snu.ac.kr

Received 6 April 2012       Accepted 25 May 2012

Copyright © 2012 Korean Endocrine Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background

The aim of this study is to investigate the distribution of plasma cholesterol and triglyceride levels as well as the prevalence of dyslipidemia among Korean adolescents.

Methods

We analyzed data for 3,045 adolescents aged 10-18 years (1,622 boys and 1,423 girls) who participated in the Korea National Health and Nutrition Examination Surveys from 2007 to 2010.

Results

The mean values of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were 159, 89, 89, and 52 mg/dL, respectively. Plasma cholesterol levels were significantly higher in girls than those in boys (162.1 mg/dL vs. 155.6 mg/dL, P < 0.0001). The 90th percentile values of total cholesterol, triglycerides, and LDL-C were 192, 149, 117 mg/dL for boys, and 195, 147, 119 mg/dL for girls. The 10th percentile value of HDL-C was 38 mg/dL for boys and 40 mg/dL for girls. Triglyceride, LDL-C cholesterol levels increased, whereas plasma HDL-C levels decreased with increasing the body mass index (P < 0.0001) in both genders. Total cholesterol levels significantly increased with increasing the body mass index, especially in boys (P < 0.0001). The prevalence of dyslipidemia was 25.2% for boys and 21.7% for girls; this value significantly increased with overweight (37-40%) and obesity (53-56%). Independent predictors (odds ratio) of dyslipidemia were age (1.49), overweight (2.06), and obesity (5.11) for boys; overweight (1.95) and obesity (3.22) for girls.

Conclusion

Adolescent dyslipidemia is strongly associated with obesity. Lipid screening for overweight or obese youths should be emphasized. Further, longitudinal studies examining the impact of childhood obesity and dyslipidemia on subsequent cardiovascular diseases are needed.

Keywords: Adolescence, Dyslipidemia, Lipids, Obesity, Prevalence

Figures and Tables

Fig. 1
Prevalence of dyslipidemia stratified by body mass index (BMI) and age.
enm-27-208-g001
Table 1
General characteristics of the participants
enm-27-208-i001

Values are expressed as mean ± SD or number (%).

BMI, body mass index; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; WC, waist circumference.

Table 2
Distributions of cholesterol and triglyceride levels by gender and age
enm-27-208-i002

HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.

Table 3
Mean values of cholesterol and triglycerides by body mass index
enm-27-208-i003

HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol.

Table 4
Prevalence of dyslipidemia by body mass index
enm-27-208-i004

Values are expressed as percentage.

*Total cholesterol > 200 mg/dL; †Triglycerides > 150 mg/dL; ‡LDL-cholesterol > 130 mg/dL; §HDL-cholesterol < 40 mg/dL; ∥Having at least one of the lipid profiles among hypercholesterolemia, hypertriglyceridemia, hyper-LDL cholesterol and hypo-HDL-cholesterol.

HDL, high-density lipoprotein; LDL, low-density lipoprotein.

Table 5
Independent risk factors for dyslipidemia
enm-27-208-i005

*Energy intake-adjusted odds ratios for dyslipidemia by multivariate logistic regression analyses.

BMI, body mass index; CI, confidence intervals; OR, odds ratio.

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