Journal List > Endocrinol Metab > v.27(2) > 1085946

Endocrinol Metab. 2012 Jun;27(2):155-158. Korean.
Published online June 20, 2012.
Copyright © 2012 Korean Endocrine Society
Visual Seizure: A Reversible Complication of Non-Ketotic Hyperglycemia
Na-Young Kim and Min Su Park
Department of Neurology, Yeungnam University College of Medicine, Daegu, Korea.

Corresponding author: Min Su Park. Department of Neurology, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu 705-717, Korea. Tel: +82-53-620-3685, Fax: +82-53-627-1688, Email:
Received October 24, 2011; Accepted January 11, 2012.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 65-year-old man with diabetes mellitus was presented with left visual aura, followed by a versive seizure, each lasting approximately 3 minutes. Neurological examination showed an intermittent left homonymous hemianopsia. Brain magnetic resonance imaging (MRI) showed right occipital lobe lesion, with cytotoxic edema. Blood glucose was 593 mg/dL and serum osmolarity was 309 mOsm/kg. The seizures were controlled by normalization of blood sugar and short-term anticonvulsant, and the lesions were resolved in a follow-up MRI. We report a case of visual seizures associated with non-ketotic hyperglycemia.

Keywords: Diabetes mellitus; Nonketotic hyperglycemia; Visual seizure


Fig. 1
Brain magnetic resonance imaging obtained at the 7th day after the symptoms onset. T2-weighted (A) and fluid attenuated inversion recovery image (B) show right occipital cortical hyperintensities and subcortical hypointensities and diffusion-weighted image (C) and apparent diffusion coefficient (D) demonstrate restricted D diffusion.
Click for larger image

Fig. 2
Follow-up brain magnetic resonance imaging obtained at the 39th day after the onset of symptoms. Fluid attenuated inversion recovery image (A), diffusion-weighted image (B) and apparent diffusion coefficient (C) show resolution of previous abnormal signal intensity lesion.
Click for larger image

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