Given the global impact of the AIDS pandemic, it is necessary to take every measure to prevent an epidemic of this disease in Korea. The only available strategy is prevention. Considering college students as a potential risk group, this study examined their knowledge of, and attitudes toward AIDS. In this study, 399 students from three colleges in Pusan and Uoolsan were examined for their attitudes to, and knowledge of AIDS. Findings indicate that the majority of the students(90%) had basic knowledge on the transmission and the prevention of the disease. However, most of them, including nursing students, lacked knowledge as to the etiological agent, major symptoms and available diagnostic techniques. To the questions designed to examine social attitude towards AIDS patients, the students showed a tendency to view AIDS patients as responsible for their own illness. Interestingly, they showed sympathy to their imaginary friends and relatives suffering from AIDS. The study findings suggest a need for the development of AIDS educational programs for college students.