Abstract
Background
Methods
Results
Figures and Tables
Fig. 1
Flow diagram of the localization strategies used to identify endogenous hyperinsulinemic hypoglycemia (EHH) patients. OGTT, oral glucose tolerance test; CT, computed tomography; MRI, magnetic resonance imaging; EUS, endoscopic ultrasound; THPVS, trans-hepatic portal vein sampling; SACS, selective arterial calcium stimulation.
![dmj-39-126-g001](/upload/SynapseData/ArticleImage/2004dmj/dmj-39-126-g001.jpg)
Fig. 2
Plasma insulin levels in patients diagnosed with insulinoma, nesidioblastosis, and insulin autoimmune syndrome (IAS). The case indicted by the arrow demonstrated positive results on the insulin autoantibody test (3,000 µIU/mL, case no. 9 in Table 2). The other case indicated by the head of arrow demonstrated negative results on the insulin autoantibody test (5 µIU/mL, case no. 10 in Table 2).
![dmj-39-126-g002](/upload/SynapseData/ArticleImage/2004dmj/dmj-39-126-g002.jpg)
Table 1
Clinical and biochemical characteristics of patients with insulinoma, nesidioblastosis, and insulin autoimmune syndrome
![dmj-39-126-i001](/upload/SynapseData/ArticleImage/2004dmj/dmj-39-126-i001.jpg)
Values are presented as median (range) or number (%).
IAS, insulin autoimmune syndrome; OGTT, oral glucose tolerance test.
aNumber of patients who developed autonomic hypoglycemic symptoms (e.g., sweating, palpitation, anxiety, hunger, nausea, and paresthesia), bNumber of patients who developed neuroglycopenic hypoglycemic symptoms (e.g., loss of consciousness, disorientation, fatigue, seizure, hypersomnia, blurred vision, and change in behavior), cNumber of patients who developed hypoglycemia on 72-hour fasting test/total number of patients who received a 72-hour fasting test, dNumber of patients who developed hypoglycemia during OGTT/total number of patients who underwent OGTT, eStatistically significant development of hypoglycemia on 72-hour fasting test.
Table 2
Characteristics of patients with insulin autoimmune syndrome and nesidioblastosis
![dmj-39-126-i002](/upload/SynapseData/ArticleImage/2004dmj/dmj-39-126-i002.jpg)