Journal List > J Korean Dent Soc Anesthesiol > v.13(3) > 1084337

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Ko, Hong, Yoon, Yoon, Lee, and Kim: Desflurane Inhalation Provide Cardiovascular Stability During Intubation but Prevention of Rocuronium Injection Pain
Original Article

Journal of the Korean Dental Society of Anesthesiology 2013; 13(3): 117-120.

Published online: 27 May 2016

DOI: https://doi.org/10.17245/jkdsa.2013.13.3.117

Desflurane Inhalation Provide Cardiovascular Stability During Intubation but Prevention of Rocuronium Injection Pain

Hyun-Min Ko, Hun-Pyo Hong, Ji-Young Yoon, Ji-Uk Yoon*, Do-Won Lee*, Cheul-Hong Kim

Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Pusan National University Dental Hospital, Dental Research Institute, Yangsan, Korea.

*Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, Busan, Korea.

Corresponding Author: Cheul-Hong Kim, 626-787 Pusan national university dental hospital, 20 Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsanman-do, Korea. Tel: +82.55.360.5370, 5117, Fax: +82.51-242-7466, anekch@pusan.ac.kr

Received 26 September 2013       Revised 1 October 2013       Accepted 1 October 2013

Copyright © 2013 Journal of the Korean Dental Society of Anesthesiology

(open-access, http://creativecommons.org/licenses/by-nc/3.0/):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background

Desflurane has very short induction time because its physical characteristics. But its pungent odor and tendency to irritate the upper airway make it unsuitable for induction of anesthesia. This study was performed to determine what time is prefer to start the desflurane inhalation.

Methods

Forty adults (17-45 years) were enrolled in a randomized, double-blind study. Twenty start desflurane inhalation just after loss of consciousness, and the others received desflurane after intubation. We monitored vital signs, BIS, desflurane concentration, rocuronium injection pain response, and airway irritation signs.

Results

The demographic data were not different two groups. Early inhalation group showed more stable cardiovascular response than that of late inhalation group. But rocuronium injection pain response and airway irritation sings were not different between two groups.

Conclusions

Early inhalation of desflurane (6 vol%) just after loss of consciousness attenuates cardiovascular responses during intubation.

Keywords: Airway irritation, Cardiovascular stability, Desflurane inhalation, Rocuronium injection pain

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