Journal List > Urogenit Tract Infect > v.11(1) > 1084199

Shin and Park: Tuberculosis of the Glans Penis Presenting as Glans Gangrene

Abstract

Tuberculosis of the glans penis is rare. The clinical features of tuberculosis of the glans penis include the appearance of a superficial ulcer of the glans. We recently experienced a case of tuberculosis of the glans penis presenting as an ulcer, which progressed to glans necrosis. A 46-year-old man presented at our institution with painful ulcerative penile lesions. Initial pathological findings of the ulcers showed non-granulomatous inflammatory changes. He was treated with antibiotics and anti-inflammatory drugs for 6 months, and during that time, his glans ulcers progressed to glans gangrene. A partial glansectomy showed multiple epithelioid granulomas with central caseous necrosis, which was compatible with the findings of tuberculosis. The patient received anti-tuberculosis chemotherapy. The current case is reported to alert physicians to consider the possibility of tuberculosis when evaluating unusual penile glans lesions.

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Fig. 1.
His glans shows two painful adjacent 12×8 mm sized ulcers with peripheral dusky areas.
uti-11-36f1.tif
Fig. 2.
His glans lesions progressed to glans gangrene.
uti-11-36f2.tif
Fig. 3.
(A) Chronic granulomatous inflammatory lesions in epithelial cells with central caseation necrosis (arrow; H&E stain, ×100). (B) Multinucleated giant Langerhan's cells (arrowhead; H&E stain, ×400).
uti-11-36f3.tif
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