Pulmonary Thromboembolism after Intravenous Immunoglobulin Therapy in Guillain-Barre Syndrome

Jin-Mo Park; Nam Kyun Kim; Jin-Sung Park

doi:10.14253/kjcn.2016.18.1.14

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Park, Kim, and Park: Pulmonary Thromboembolism after Intravenous Immunoglobulin Therapy in Guillain-Barre Syndrome

Case Report

J Korean Ophthalmol Soc 2016;18(1):14-17.

Published online: 18 January 2016

DOI: https://doi.org/10.14253/kjcn.2016.18.1.14

Pulmonary Thromboembolism after Intravenous Immunoglobulin Therapy in Guillain-Barre Syndrome

Jin-Mo Park¹, Nam Kyun Kim², Jin-Sung Park³

¹Department of Neurology, Dongguk University, School of Medicine, Gyeongju, Korea

²Divison of Cardiology, Department of Internal Medicine, Kyungpook National University, School of Medicine, Daegu, Korea

³Department of Neurology, Kyungpook National University, School of Medicine, Daegu, Korea

Address for correspondence; Jin-Sung Park Department of Neurology, Kyungpook National University, School of Medicine, 680 Gukchaebosang-ro, Jung-gu, Daegu 41944, Korea Tel: +82-53-200-2027 Fax: +82-53-200-2029 E-mail: jinforeva@gmail.com

Received 26 December 2015 Revised 9 May 2016 Accepted 18 May 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Intravenous immunoglobulin (IVIG) is a safe treatment to treat various neurological disorders, but fatal thrombotic events as rare complications have been reported. A 54-year-old woman with Guillain-Barre syndrome complained of dyspnea during IVIG treatment. She was finally diagnosed with pulmonary thromboembolism. To the best of our knowledge, this is the first case of pulmonary thromboembolism associated with IVIG treatment in a Korean patient with Guillain-Barre syndrome. (Korean J Clin Neurophysiol 2016;18:14-17)

Keywords: Guillain-Barre syndrome, Intravenous immunoglobulin, Pulmonary thromboembolism

REFERENCES

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Figure 1.

The baseline and follow up electrocardiography of the patient. The initial electrocardiography was unremarkable (A) but follow up electrocardiography performed after dyspnea had a significant change showing S1Q3T3 pattern (prominent S wave in lead I, Q wave and inverted T wave in lead III), T wave inversion in leads V1-V6 V1-V6 (thin arrows) (B), The axial sections of CT scan showed prominent bilateral pulmonary thromboembolism pulmonary thromboembolism (white arrows) (C) and a deep vein thrombosis in the left deep popliteal vein popliteal vein (white arrow) (D). CT; computed tomography.

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