Journal List > J Korean Neurotraumatol Soc > v.5(2) > 1084049

Choi, Kim, Park, Chi, Kim, and Kim: The Relation between Recurrence and Antiplatelet or Anticoagulant Agents on Chronic Subdural Hemorrhage

Abstract

Objective

The purpose of this study was to examine the corelation of the recurrence rate and the use of antiplatelet agent or anticoagulant agent on chronic subdural hematoma patient group, and to find the appropriate time that reuse the agents.

Methods

Between January 2007 and December 2008, 37 patients has undergone burr hole trephination for chronic subdural hematoma. Among them, 8 patients had been used antiplatelet or anticoagulant agent (agent using group). The other patients were agent non-using group. We reviewed medical and laboratory records retrospectively.

Results

Preoperative laboratory finding including prothrombin time (PT), activated partial thromboplastin time (aPTT), international normalized ratio (INR), bleeding time (BT) were all within normal range on agent using group. Follow up laboratory findings were also all within normal range. The recurrence rate on agent using group was not superior to agent non-using group (12.5% : 13.8%). The patients with heart problem were took medication again after drainage catheter removal (postoperative second or third day). The prescribed medicines were restarted to old cerebral infarction patients on postoperative seventh day.

Conclusion

The use of antiplatelet or anticoagulant agents are not influenced recurrence rate on chronic subdural hematoma operation if the patients have no bleeding tendency before operation. Re-administration of agents may be possible within postoperative seventh day.

Figures and Tables

TABLE 1
Characteristics of the patients use antiplatelet or anticoagulant agents
jknts-5-53-i001

No: number, MI: myocardial infarction

TABLE 2
Preoperative laboratory findings of the patients use antiplatelet or anticoagulant agents
jknts-5-53-i002

No: number, PT: prothrombin time (10-12.7 sec, 77.0-124.6%), aPTT: activated partial thromboplastin time (26.9-40.8 sec), INR: international normalized ratio (0.89-1.11), BT: bleeding time (1-4 min), s ec: second, min: minute

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