This study was performed to provide information on the relationship between admission criteria and medical school performance (MSP). Seventy six medical students admitted to the Ewha School of Medicine in 2007 were enrolled. The admission criteria included the undergraduate grade point average (GPA), medical education eligibility test (MEET), essay, letters of recommendation, and admission interview score. MSP was measured by GPA. Standard tests of bivariate correlation and multivariate regression analysis were used to examine the relationship between multiple factors of admission criteria and MSP for the first two years after admission. Among the admission criteria, scores of undergraduate GPA, essay, and letters of recommendation were significantly correlated with MSP. Admission interview score, however, had no correlation with MSP. Although total MEET score was not related with MSP as well, science reasoning-2 demonstrated significant correlation with MSP. Further studies will be needed to define the clear relationship between various admission criteria and MSP.