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Journal List > Ewha Med J > v.20(4) > 1083404

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Ko: β-glucuronidase Activity in Rheumatoid Arthritis and Osteoarthritis
Original Article

The Ewha Medical Journal 1997; 20(4): 385-390.

Published online: 24 July 2015

DOI: https://doi.org/10.12771/emj.1997.20.4.385

β-glucuronidase Activity in Rheumatoid Arthritis and Osteoarthritis

Sang Hun Ko

Department of Orthopaedic Surgery, College of Medicine, Ewha Womans University, Korea.

Copyright © 1997. Ewha Womans University School of Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives

In ostroarthritis and rheumatoid arthritis, β-glucuronidase activity was measured in body fluid to diagnose this special disease entities.

Methods

The β-glucuronidase activity was studied in the urine, serum and joint fluid. The level of this specimens were estimated by statistical sections.

Results

1) The β-glucuronidase activity in urine, serum and joint fluid of osteoarthritis patients were 0.09U/l urine, 0.14U/l serum, 0.06U/l joint fluid. The highest level of activity was in the serum.
2) The β-glucuronidase activity on rheumatoid arthritis was 0.19U/l urine, 0.17U/l serum, 0.07U/l joint fluid. The highest increased level of activity was in the urine.
3) In the joint fluid and serum, there is the no mean of stistical analysis. But in the urine, there is marked meaning of statistical analysis(Male : p=0.0041, Female : p=0.0001).

Conclusion

β-glucuronidase activity was influenced by osteoarthritis and rheumatoid arthritis. Especially in the urine, β-glucuronidase activity was outstanding statistical meaning. According to disease entities, The level of activity was different from each specimen.

Keywords: Osteoarthritis, Rheumatoid arthritis, β-glucuronidase

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