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Lee: Effects of Ketamine, Halothane and Enflurane on the Awareness Under N2O for Cesarean Section
Original Article

The Ewha Medical Journal 1989; 12(4): 329-334.

Published online: 24 July 2015

DOI: https://doi.org/10.12771/emj.1989.12.4.329

Effects of Ketamine, Halothane and Enflurane on the Awareness Under N2O for Cesarean Section

Guie Yong Lee

Department of Anesthesiology, College of Medicine, Ewha Womans University, Korea.

Corresponding author: Guie Young Lee. Department of Anesthesiology, College of Medicine, Ewha Womans University, Korea.

Copyright © 1989. Ewha Womans University School of Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A major problem with general anesthesia for Cesarean section is the incidence of maternal awareness and unpleasant recall occasioned by the use small doses and low concentrations of anesthetics to minimize neonatal effect.
To reduce awareness, various measures have been attempted. The purpose of study is to assess the influence of ketamine, halothane and enflurane on the maternal awareness and neonatal depression under N2O for Cesarean section. This study group consisted of 48 patients undergoing Cesarean section under general anesthesia.
Anesthesia was induced by thiopental, succinylcholine chloride injected, and maintained until baby delivery with according to divided group.
Group 1: thiopental, 50% N20
Group 2: thiopental, 50% N2O and ketamine(0.25mg/kg)
Group 3: thiopental, 50% N2O and 0.5% halothane
Group 4: thiopental, 50% N20 and 0.6% enflurane
The results were as follows :
1. The incidence of awareness of 50% N2O group was 66.7%.
2. The incidence of awareness of ketamine, halothane and enflurane group was 8.3%.
3. When induction-delivery time is 8 minutes or less, there was no correlation between induction-delivery time and awareness.
4. There was no neonatal depression.
The use of ketamine, halothane and enflurane appears to be effective in preventing awareness when induction-delivery time is 8 minutes or less.

Keywords: Cesarean section, Acareness, Ketamine, Halothane, Enflurane

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