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Abstract
We describe here two Graves' patients who have presented with atypical symptoms. Interestingly, both of them had symptoms related to imbalance of body fluid homeostasis. Chief complaint of a 35-year-old woman (case 1) was the ipsilateral edema of upper body. A 33-year-old man (case 2) who had severe polyuria has referred from urology department with impression of diabetes insipidus. Both of them denied any typical symptoms of Graves' disease at presentation. These rare extrathyroid manifestations of Graves' disease were completely subsided after antithyroid drug treatment. We introduce their clinical courses and possible pathophysiological mechanisms of the atypical symptoms of Graves' disease.
References
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Fig. 1.
Left dominant ipsila-teral edema of upper ex-tremity (case 1) at presen-tation (A), after 6 months antithyroid drug treatment (B).
Fig. 2.
Computed tomography of the case 1. Initial CT scans (A) showed diffuse increased soft tissue density in anterior mediastinum (A. long arrows), multiple lymph node enlargement in left axillary (A. short arrow) and ipsilateral edema in upper trunk (B). Follow-up CT scans after 6 months antithyroid drug treatment showed significantly decreased extent of soft tissue density in anterior mediastinum (C. long arrows), lymph node enlargement in left axillary (C. short arrow) and improved edema in upper trunk (D).
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