Journal List > Asian Oncol Nurs > v.17(3) > 1081900

Seo and Yi: A Study on Genetic Knowledge and Anxiety in Patients with Breast Cancer

초록

Purpose

The purpose of the study was to understand the levels of knowledge about hereditary breast cancer and anxiety among patients with breast cancer and to identify the relationship between knowledge and anxiety.

Methods

The data were collected from 100 patients with breast cancer in Seoul in 2013. A 15-item hereditary breast cancer knowledge questionnaire and 20-item anxiety state questionnaire were used to measure knowledge and anxiety, respectively. The data were analyzed using descriptive statistics, t-tests, one-way ANOVA, LSD post hoc tests, and Cronbach's α tests in SPSS/WIN 21.0.

Results

The mean score of knowledge was 8.34±3.17, indicating 0.56 when converted to 1. Knowledge was different by age, education, marital status, monthly family income, risk for hereditary breast cancer, and needs for genetic counseling. The mean score of anxiety was 46.05±10.53. There was positive correlation between knowledge and anxiety (r=.25, p=.014).

Conclusion

The results of this study indicate that oncology professionals need to provide genetic knowledge for early detection and prevention of secondary cancer to patients with breast cancer, while con-sidering and relieving their emotional distress, such as anxiety.

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Table 1.
Knowledge and Anxiety by General Characteristics (N=100)
Variables Categories n (%) or M ± SD Knowledge Anxiety
M ± SD t or F p M ± SD t or F p
Age (year) 20~29 5 (5.0) 9.80 ± 3.96 3.56 .009 41.80 ± 7.19 1.18 .325
  30~39 21 (21.0) 9.52 ± 3.16     49.67 ± 10.54    
  40~49 39 (39.0) 8.72 ± 2.92     45.92 ± 11.53    
  50~59 23 (23.0) 7.57 ± 3.01     46.96 ± 8.74    
  ≥ 60 12 (12.0) 5.92 ± 2.71     42.67 ± 10.31    
    46.4 ± 10.79            
Religion Christianity 20 (20.0) 7.75 ± 3.63 1.93 .130 43.15 ± 12.92 1.64 .185
  Catholicism 19 (19.0) 9.84 ± 2.73     48.79 ± 12.13    
  Buddhism 33 (33.0) 8.24 ± 2.93     48.33 ± 9.35    
  Others 28 (28.0) 7.86 ± 3.23     44.64 ± 7.93    
Education ≤ Middle school 16 (16.0) 6.88 ± 3.32 5.94 .004 45.06 ± 8.53 0.49 .616
  High school 34 (34.0) 7.53 ± 2.98     45.44 ± 10.44    
  ≥ College 50 (50.0) 9.36 ± 2.96     47.38 ± 11.11    
Occupation Yes 40 (40.0) 8.76 ± 3.30 -1.06 .294 46.10 ± 10.78 0.19 .847
  No 60 (60.0) 8.07 ± 3.08     46.52 ± 10.34    
Marital status Married 76 (76.0) 8.18 ± 3.07 3.10 .050 47.25 ± 10.70 1.18 .312
  Unmarried 16 (16.0) 9.88 ± 3.18     43.63 ± 9.05    
  Others 8 (8.0) 6.75 ± 3.50     43.25 ± 10.46    
Monthly family income (10,000 won) <200 22 (22.0) 6.90 ± 3.25 4.82 .010 43.77 ± 8.36 2.66 .075
200~399 43 (43.0) 8.16 ± 3.26 45.09 ± 9.59
≥ 400 35 (35.0) 9.46 ± 2.65     49.51 ± 12.07    
Risk for hereditary Low risk group 44 (44.0) 7.59 ± 3.16 -2.13 .036 44.89 ± 9.30 -1.24 .217
breast cancer High risk group 56 (56.0) 8.93 ± 3.09     47.50 ± 11.25    
Needs for genetic Yes 70 (70.0) 8.77 ± 3.08 2.11 .037 46.40 ± 11.05 -0.07 .942
counseling No 30 (30.0) 7.33 ± 3.21     46.23 ± 9.13    

LSD= Least significance difference.

Table 2.
Knowledge Scores of Each Question (N=100)
Question M ± SD
·The need of family surveillance of the person not carrying mutation. 0.88 ± 0.37
·The possibility of the breast cancer in the case of the women not carrying mutation. 0.85 ± 0.36
·The need of the breast self examination and the mammogram for women not carrying mutation. 0.82 ± 0.39
·The onset age of the breast cancer of the women with positive mutation. 0.65 ± 0.48
·In the case of the women not having mutation, the possibility of the predisposing to hereditary breast and ovarian cancer in her family. 0.60 ± 0.49
·The tendency of the young age onset in the case of the women with mutation. 0.59 ± 0.49
·The possibility of the collateral breast cancer of the women with mutation. 0.54 ± 0.50
·The possibility of the mutation detection in mammogram. 0.53 ± 0.50
·The relationship of breast cancer between mother and daughter. 0.53 ± 0.50
·The need of the ovarian surveillance for the women having mutation. 0.51 ± 0.50
·The possibility of the son's having breast cancer, if his mother has mutation. 0.48 ± 0.50
·The ratio of the hereditary breast and ovarian cancer among the breast cancer population. 0.44 ± 0.50
·The possibility of the daughter's having mutation, if her father has mutation. 0.40 ± 0.49
·The relationship of hereditary breast and ovarian cancer between mother and daughter. 0.28 ± 0.45
·The possibility of the daughter's having mutation, if her mother has mutation. 0.25 ± 0.44
Sum (15 items) 8.34 ± 3.17
Total M ± SD 0.56 ± 0.21
Table 3.
Level of Anxiety (N=100)
Variable M ± SD Actual range Possible range
Anxiety score 46.05 ± 10.53 24~74 20~80
Table 4.
Relationship between Knowledge and Anxiety of the Participants
Variable Anxiety r p
Knowledge .25 .014
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