Impact of Climacteric Symptoms and Fatigue on the Quality of Life in Breast Cancer Survivors: The Mediating Effect of Cognitive Dysfunction

Gyung Duck Kim

doi:10.5388/aon.2014.14.2.58

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Kim: Impact of Climacteric Symptoms and Fatigue on the Quality of Life in Breast Cancer Survivors: The Mediating Effect of Cognitive Dysfunction

Original Article

Asian Oncology Nursing 2014; 14(2): 58-65.

Published online: 30 June 2014

DOI: https://doi.org/10.5388/aon.2014.14.2.58

Impact of Climacteric Symptoms and Fatigue on the Quality of Life in Breast Cancer Survivors: The Mediating Effect of Cognitive Dysfunction

Gyung Duck Kim

Department of Nursing, Dongyang University, Yeongju, Korea.

Address reprint requests to: Kim, Gyung Duck. Department of Nursing, Dongyang University, 145 Dongyang-daero, Punggi-eup, Yeongju 750-711, Korea. Tel: +82-54-630-1373, Fax: +82-54-630-1371, gdkim@dyu.ac.kr

Received 12 May 2014 Accepted 26 June 2014

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to test hypothetical model of quality of life (QOL) in breast cancer survivors and to test the mediating effects of cognitive dysfunction.

Methods

This study was conducted from December 1st, 2013 to February 28th, 2014. 164 breast cancer survivors were recruited from A, D, and Y city in Korea. The instruments used in this study were climacteric symptoms, fatigue, cognitive dysfunction, and the QOL scales. Data were analyzed using descriptive statistics, correlation, and pathway.

Results

Cognitive dysfunction was directly affected by climacteric symptoms and fatigue. QOL was directly affected by fatigue, However climacteric symptoms and cognitive dysfunction did not effect on QOL directly. Impact of climacteric symptoms on QOL, mediating effect of cognitive dysfunction was not confirmed. In addition, effect of fatigue on the QOL, the mediating effect of cognitive dysfunction was not.

Conclusions

Effects of climacteric symptoms on QOL was not mediated by cognitive dysfunction, Furthermore effects of fatigue on QOL was not mediated by cognitive dysfunction.

Keywords: Breast Neoplasms, Climacteric Symptoms, Fatigue, Cognitive Dysfunction, Quality of Life

Figures and Tables

Fig. 1

Conceptual framework.

Fig. 2

Pathway model of climacteric symptoms, fatigue, cognitive dysfunction, and quality of life.

Table 1

Score of Climacteric Symptoms, Fatigue, Cognitive Dysfunction, and Quality of Life (N=164)

PWB=Physical well-being; SWB=Social well-being; EWB=Emotional well-being; FWB=Functional well-being; BCS=Breast Cancer Subscale.

Table 2

Correlation between Climacteric Symptoms, Fatigue, Cognitive Dysfunction, and Quality of Life (N=164)

^*p<.01.

Table 3

Total Effect, Direct Effect, and Indirect Effect

SE=Standardized estimate; CR=Critical ratio; SMC=Squared multiple correlation.

^*p<.05, ^†p<.001.

Notes

This research was supported by Dongyang University Research Fund 2013.

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