A Symptom Cluster Analysis of Breast Cancer Patients Using a Mediation Model

Gyung Duck Kim; Hyun Jin Jang

doi:10.5388/aon.2012.12.4.274

Journal List > Asian Oncol Nurs > v.12(4) > 1081745

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Kim and Jang: A Symptom Cluster Analysis of Breast Cancer Patients Using a Mediation Model

Original Article

Asian Oncology Nursing

Asian Oncology Nursing 2012; 12(4): 274-279.

Published online: 31 December 2012

DOI: https://doi.org/10.5388/aon.2012.12.4.274

A Symptom Cluster Analysis of Breast Cancer Patients Using a Mediation Model

Gyung Duck Kim¹, Hyun Jin Jang²

¹Department of Nursing, Dongyang University, Yeongju, Korea.

²Pancreaticobiliary Cancer Clinic, Severance Hospital, Seoul, Korea.

Address reprint requests to: Jang, Hyun Jin. Pancreaticobiliary Cancer Clinic, Severance Hospital, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea. Tel: +82-2-2228-5419, Fax: +82-2-2227-7934, jini1833@yuhs.ac

Received 4 November 2012 Accepted 6 December 2012

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

This study was conducted to test whether sleep disturbance mediates the effect of pain on fatigue, whether fatigue mediates the effect of pain on depression, and whether fatigue mediates the effect of sleep disturbance on depression.

Methods

This study was conducted from September 12th to December 20th, 2011. One hundred eighty-eight breast cancer patients were recruited from D city and S city in Korea. The instruments used in this study were the pain, sleep disturbance, fatigue, and depression scales. Data were analyzed using descriptive statistics, Pearson correlation coefficients, and mediation pathway with the SPSS 12.0 and AMOS 20.0 programs.

Results

There was correlation among pain, fatigue, sleep disturbance, and depression. Mediation analyses indicated that pain influences fatigue. sleep disturbance, and depression directly as well as indirectly. Sleep disturbance influences fatigue and depression directly, also fatigue influences depression directly. But sleep disturbance had no direct effect on depression.

Conclusion

Significant correlations among the four symptoms supported the existence of the symptom cluster. Effects of pain on fatigue was partially mediated by sleep disturbance, also effects of pain on depression was partially mediated by fatigue. However, the effects of sleep disturbance on depression was fully mediated by fatigue.

Keywords: Breast Neoplasms, Mediation, Symptoms

Figures and Tables

Fig. 1

Conceptual framework.

Fig. 2

Pathway model of pain, sleep disturbance, fatigue, and depression. ^*p<.05, ^†p<.001.

Table 1

The Score of Pain, Fatigue, Sleep Disturbance, and Depression Symptom (N=188)

Table 2

Correlation among Pain, Fatigue, Sleep Disturbance, and Depression (N=188)

Table 3

Total Effect, Direct Effect, and Indirect Effect

Notes

The present research has been supported by Korea Breast Cancer Foundation.

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