Journal List > Asian Oncol Nurs > v.12(3) > 1081736

Kim: Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy

Abstract

Purpose

The purpose of this study was to identify factors that influence medication adherence in colorectal cancer patients receiving oral chemotherapy.

Methods

One hundred and nine colorectal cancer patients receiving oral chemotherapy were recruited in the cross-sectional survey design. A survey including medication adherence, knowledge about chemotherapy, self-efficacy, depression and symptom experience were completed.

Results

The level of medication adherence was 7.38±.80. Medication adherence showed significant differences according to perceived health status and combination of IV chemotherapy. Medication adherence was significant correlated with self-efficacy, depression and symptom experience. On stepwise regression analysis, the most important factors related to the medication adherence were symptom experience, perceived health status and combination of IV chemotherapy. These variables explained 17% of medication adherence.

Conclusion

The level of medication adherence in colorectal cancer patients receiving oral chemotherapy was relatively high. It is important to develop nursing intervention for medication adherence in colorectal cancer patients that focus on symptom experience and to consider about perceived health status and combination of IV chemotherapy.

Figures and Tables

Table 1
Medication Adherence by Scoiodemographic and Disease related Characteristics (N=109)
aon-12-213-i001

a,b,cScheffe's grouping.

ECOG PS=Eastern Cooperative Oncology Group performance status; IV=Intravenous.

Table 2
Means and Standard Deviation of Knowledge about Chemotherapy, Self-efficacy, Depression, Symptom Experience and Medication Adherence (N=109)
aon-12-213-i002
Table 3
Correlation among Medication Adherence, Knowledge about Chemotherapy, Self-efficacy, Depression, and Symptom Experience (N=109)
aon-12-213-i003
Table 4
Affecting Factors on Medication Adherence by Stepwise Multiple Regression (N=109)
aon-12-213-i004

VIF=Variance inflation factor; IV=Intravenous.

Notes

This article is an addition based on the first author's doctoral thesis from Chung-Ang University.

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