Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy

Jeong Hye Kim

doi:10.5388/aon.2012.12.3.213

Journal List > Asian Oncol Nurs > v.12(3) > 1081736

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Kim: Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy

Original Article

Asian Oncology Nursing

Asian Oncology Nursing 2012; 12(3): 213-220.

Published online: 30 September 2012

DOI: https://doi.org/10.5388/aon.2012.12.3.213

Influencing Factors on Medication Adherence in Colorectal Cancer Patients Receiving Oral Chemotherapy

Jeong Hye Kim

Department of Nursing, Asan Medical Center, Seoul, Korea.

Address reprint requests to: Kim, Jeong Hye. Department of Nursing, Asan Medical Center, 86 Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-6872, Fax: +82-2-3010-6874, kimjh@amc.seoul.kr

Received 20 August 2012 Accepted 8 September 2012

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to identify factors that influence medication adherence in colorectal cancer patients receiving oral chemotherapy.

Methods

One hundred and nine colorectal cancer patients receiving oral chemotherapy were recruited in the cross-sectional survey design. A survey including medication adherence, knowledge about chemotherapy, self-efficacy, depression and symptom experience were completed.

Results

The level of medication adherence was 7.38±.80. Medication adherence showed significant differences according to perceived health status and combination of IV chemotherapy. Medication adherence was significant correlated with self-efficacy, depression and symptom experience. On stepwise regression analysis, the most important factors related to the medication adherence were symptom experience, perceived health status and combination of IV chemotherapy. These variables explained 17% of medication adherence.

Conclusion

The level of medication adherence in colorectal cancer patients receiving oral chemotherapy was relatively high. It is important to develop nursing intervention for medication adherence in colorectal cancer patients that focus on symptom experience and to consider about perceived health status and combination of IV chemotherapy.

Keywords: Chemotherapy, Medication Adherence, Colorectal Neoplasms

Figures and Tables

Table 1

Medication Adherence by Scoiodemographic and Disease related Characteristics (N=109)

^a,b,cScheffe's grouping.

ECOG PS=Eastern Cooperative Oncology Group performance status; IV=Intravenous.

Table 2

Means and Standard Deviation of Knowledge about Chemotherapy, Self-efficacy, Depression, Symptom Experience and Medication Adherence (N=109)

Table 3

Correlation among Medication Adherence, Knowledge about Chemotherapy, Self-efficacy, Depression, and Symptom Experience (N=109)

Table 4

Affecting Factors on Medication Adherence by Stepwise Multiple Regression (N=109)

VIF=Variance inflation factor; IV=Intravenous.

Notes

This article is an addition based on the first author's doctoral thesis from Chung-Ang University.

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