Effects of Pain, Sleep Disturbance, and Fatigue on the Quality of Life in Patients with Pancreatic Cancer Undergoing Chemotherapy

Gyung Duck Kim; Hyun Jin Jang

doi:10.5388/aon.2012.12.2.117

Journal List > Asian Oncol Nurs > v.12(2) > 1081722

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Kim and Jang: Effects of Pain, Sleep Disturbance, and Fatigue on the Quality of Life in Patients with Pancreatic Cancer Undergoing Chemotherapy

Original Article

Asian Oncology Nursing

Asian Oncology Nursing 2012; 12(2): 117-124.

Published online: 30 June 2012

DOI: https://doi.org/10.5388/aon.2012.12.2.117

Effects of Pain, Sleep Disturbance, and Fatigue on the Quality of Life in Patients with Pancreatic Cancer Undergoing Chemotherapy

Gyung Duck Kim¹, Hyun Jin Jang²

¹Department of Nursing, Dongyang University, Yeongju, Korea.

²Pancreaticobiliary Cancer Clinic, Severance Hospital, Seoul, Korea.

Address reprint requests to: Kim, Gyung Duck. Department of Nursing, Dongyang University, 145 Dongyang-daero, Punggi-eup, Yeongju 750-711, Korea. Tel: +82-54-630-1373, Fax: +82-54-630-1371, gdkim@dyu.ac.kr

Received 23 March 2012 Accepted 21 May 2012

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to assess pain, sleep disturbance, fatigue, and the quality of life and to identify the impact of pain, sleep disturbance and fatigue on the quality of life in patients with pancreatic cancer undergoing chemotherapy.

Methods

Data were collected from June to July, 2010. Participants were recruited from Y university hospital in Seoul. Research instruments included numeric rating scale for pain, Functional Assessment Chronic Illness Therapy-Functional Well-Being (FACIT-FWB): General Factor 5 (GF5) for sleep disturbance, Functional Assessment of Cancer Therapy-General (FACT-G) for quality of life, and FACT-Fatigue for fatigue.

Results

The quality of life for cancer patients had a significant relationship with pain, sleep disturbance, and fatigue. The significant factors influencing quality of life were pain, sleep disturbance, and fatigue that explained 52.6% of the variance.

Conclusion

Patients with pancreatic cancer undergoing chemotherapy experienced pain, fatigue, and sleep disturbance which led to a negative effect on quality of life. The results suggest that intervention program to improve quality of life could reduce pain, fatigue, and sleep disturbance of pancreatic cancer patients undergoing chemotherapy.

Keywords: Pancreatic Neoplasms, Pain, Sleep Disorders, Fatigue, Quality of Life

Figures and Tables

Table 1

The Score of Pain, Fatigue, Sleep Disturbance and Quality of life (N=121)

PWB=physical well-being; SWB=social well-being; EWB=emotional well-being; FWB=functional well-being.

Table 2

Correlation among Pain, Sleep Disturbance, Fatigue, and Quality of Life (N=121)

Table 3

The Difference of Fatigue and Quality of Life to Characteristics (N=121)

OP=Operation; RT=Radiotherapy.

Table 4

Effects of Pain, Sleep Disturbance, and Fatigue on the Quality of Life

PWB=physical well-being; SWB=social well-being; EWB=emotional well-being; FWB=functional well-being.

References

1. National Cancer Information Center. National Cancer Statistics. accessed on 25 May 2011. Available at: http://www.cancer.go.kr/cms/statics/survival_rate/index.html/.

2. Choi CM. A study on quality of life of advanced hepatobiliary and pancreatic cancer patients who administered for traditional korean cancer treatment [dissertation]. 2008. Seoul: Kyunghee Univ..

3. Song SY. Pancreatic cancer guide book. 2007. Seoul: kugilmedia.

4. Reyes-Gibby CC, Chan W, Abbruzzese JL, Xiong HQ, Ho L, Evans DB, et al. Patterns of self-reported symptoms in pancreatic cancer patients receiving chemoradiation. J Pain Symptom Manage. 2007. 34:244–252.

5. Jia L, Jiang SM, Shang YY, Huang YX, Li YJ, Xie DR, et al. Investigation of incidence of pancreatic cancer-related depression and its relationship with the quality of life of patients. Digestion. 2010. 82(1):4–9.

6. Cho YD. Supportive care for symptom relife in pancreatic cancer. Korean J Gastroenterol. 2008. 51:119–126.

7. Song HJ. Factors affecting nurse's pain management for cancer patients [dissertation]. 2009. Seoul: Yonsei Univ..

8. Savard J, Morin CM. Insomnia in the context of cancer: A review of a neglected problem. J Clin Oncol. 2001. 19:895–908.

9. Son HG. Relationship between quality of sleep and fatigue in patients with hemato-malignancy in receiving chemotheraphy [dissertation]. 2006. Busan: Kosin Univ..

10. Crippa S, Domínguez I, Rodríguez JR, Razo O, Thayer SP, Ryan DP, et al. Quality of life in pancreatic cancer: analysis by stage and treatment. J Gastrointest Surg. 2008. 12:783–793.

11. Labori KJ, Hjermstad MJ, Wester T, Buanes T, Loge JH. Symptom profiles and palliative care in advanced pancreatic cancer: a prospective study. Support Care Cancer. 2006. 14:1126–1133.

12. Bernhard J, Dietrich D, Glimelius B, Hess V, Bodoky G, Scheithauer W, et al. Estimating prognosis and palliation based on tumour marker CA 19-9 and quality of life indicators in patients with advanced pancreatic cancer receiving chemotherapy. Br J Cancer. 2010. 103:1318–1324.

13. Jang HJ. Information needs, treatment-related decision conflict, and quality of life in pancreatic cancer patient [dissertation]. 2010. Seoul: Yonsei Univ..

14. FACIT. Functional Assessment of Chronic Illness Therapy. accessed on 1 June, 2010. Available at: http://www.facit.org/.

15. FACIT. Elmhurst: Functional Assessment of Chronic Illness Therapy. Functional Assessment of Chronic Illness Therapy-Fatigue [Internet]. accessed on 1 June, 2010. [cited 2010 June 01]. Available from: http://www.facit.org/.

16. Kim GD, Kim KH. Symptom cluster and quality of life with breast cancer undergoing chemotherapy. Korean J Adult Nurs. 2011. 23:434–445.

17. So WK, Marsh G, Ling WM, Leung FY, Lo JC, Yeung M, et al. The symptom cluster of fatigue, pain, anxiety, and depression and the effect on the quality of life of women receiving treatment for breast cancer: A multicenter study. Oncol Nurs Forum. 2009. 36:E205–E214.

18. Ryu JK. Nutrition and drug therapy of pancreatobiliary cancer progression. Korean J Pancreas Biliary Tract. 2007. 12(1):28–34.

19. Kwak MJ. A study on the relation of pain, anxiety, abd sleep in the cancer patients [dissertation]. 2001. Seoul: Ewha Womans Univ..

20. Son SK. The hopelessness of the lung cancer patient. Korean Nurse. 1995. 35(2):46–49.

21. Vena C, Parker K, Allen R, Bliwise D, Jain S, Kimble L. Sleep-wake disturbances and quality of life in patients with advanced lung cancer. Oncol Nurs Forum. 2006. 33:761–769.

22. Robinson DW, Eisenberg DF, Cella D, Zhao N, DeBoer C, DeWitte M. The prognostic significance of patient-reported outcomes in pancreatic cancer cachexia. J Support Oncol. 2008. 6:283–290.

23. Byun HS, Kim GD, Chung BY, Kim KH. Fatigue and quality of life of korean cancer inpatients. Korean J Hosp Palliat Care. 2010. 13(2):98–108.

24. Sun V, Ferrell B, Juarez G, Wagman LD, Yen Y, Chung V. Symptom concerns and quality of life in hepatobiliary cancers. Oncol Nurs Forum. 2008. 35(3):E45–E52.

25. Steel JL, Eton DT, Cella D, Olek MC, Carr BI. Clinically meaningful changes in health-related quality of life in patients diagnosed with hepatobiliary carcinoma. Ann Oncol. 2006. 17:304–312.

26. Banthia R, Malcarne VL, Ko CM, Varni JW, Sadler GR. Fatigued breast cancer survivors: The role of the sleep quality, depressed mood, stage and age. Psychol Health. 2009. 24:965–980.

27. Cheng KK, Lee DT. Effects of pain, fatigue, insomnia, and mood disturbance on functional status and quality of life of elderly patients with cancer. Crit Rev Oncol Hematol. 2011. 78:127–137.

28. Beck SL, Dudley WN, Barsevick A. Pain, sleep disturbance, and fatigue in patients with cancer: Using a mediation model to test a symptom cluster. Oncol Nurs Forum. 2005. 32:542.

TOOLS

Similar articles