Pre- and Post-Transplant Nutritional Assessment in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mi Young Park; Jeong Yun Park

doi:10.5388/aon.2012.12.1.110

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Park and Park: Pre- and Post-Transplant Nutritional Assessment in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Original Article

Asian Oncology Nursing

Asian Oncology Nursing 2012; 12(1): 110-116.

Published online: 29 February 2012

DOI: https://doi.org/10.5388/aon.2012.12.1.110

Pre- and Post-Transplant Nutritional Assessment in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Mi Young Park¹, Jeong Yun Park²

¹Nurse, Asan Medical Center, Seoul, Korea.

²Assistant Professor, Department of Clinical Nursing, University of Ulsan, Seoul, Korea.

Address reprint requests to: Park, Jeong Yun. Department of Clinical Nursing, University of Ulsan, 86 Asanbyeongwon-gil, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-5333, Fax: +82-2-3010-5332, pjyun@ulsan.ac.kr

Received 10 December 2011 Accepted 1 February 2012

Abstract

Purpose

This study was performed to identify the pre-and post-transplant nutritional assessment for patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).

Methods

The subjects of this study were 25 patients undergoing allogeneic HSCT. The data collection was performed from January 31st to March 31st, 2011. The Patient-Generated Subjective Global Assessment (PG-SGA), anthropometrics and biochemical test were collected from the time they entered the isolation unit until they left.

Results

Pre-transplant nutritional assessment status indicated moderate malnutrition which scored 7.32±1.68 in PG-SGA. There were 22 patients (88.0%) with moderate malnutrition and 3 patients (12.0%) with severe malnutrition. Post-transplant nutritional assessment indicated severe malnutrition status which scored 11.92±3.26 in PG-SGA. Pre-and post-transplant nutritional assessment displayed significant differences (p<.001) in PG-SGA score. Hematopoietic stem cell transplantation led to a deterioration of patients' nutritional status. Pre-transplant patients were already in malnutrition status and patients undergoing allogeneic HSCT were at risk for malnutrition.

Conclusion

Pre- and post-transplant patients were categorized as having undernutritional and malnutritional status. Pre-transplant nutrition status impacted on post-transplant nutritional status. Health care personnel should pay attention to patient's nutrition status when undergoing allogeneic HSCT with appropriate nutritional assessment tools.

Keywords: Nutritional Status, Hematopoietic Stem Cell Transplantation, PG-SGA Tool

Figures and Tables

Table 1

Sociodemographic and Clinical Characteristics of Patients (N=25)

^*M±SD=42.0±13.7.

Table 2

Pre-transplant nutritional assessment using PG-SGA, anthropometrics, biochemical indices (N=25)

PG-SGA=Patient-Generated Subjective Global Assessment; TSF=triceps skinfold thickness; MAMC=midarm muscle circumference.

Table 3

Post-transplant nutritional assessment using PG-SGA, anthropometrics, biochemical indices (N=25)

PG-SGA=Patient-Generated Subjective Global Assessment; TSF=triceps skinfold thickness; MAMC=midarm muscle circumference.

Table 4

Pre-and post-transplant nutritional assessment in scored PG-SGA, anthropometrics, biochemical indices (N=25)

^*Fisher' exact test.

PG-SGA=Patient-Generated Subjective Global Assessment; TSF=triceps skinfolds thickness; MAMC=midarm muscle circumference.

Notes

This article is a revision of the first author's master's thesis from University of Ulsan.

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