Journal List > J Nutr Health > v.48(2) > 1081378

J Nutr Health. 2015 Apr;48(2):123-132. Korean.
Published online April 30, 2015.  https://doi.org/10.4163/jnh.2015.48.2.123
© 2015 The Korean Nutrition Society
Anti-obesity effect of Korean Hamcho (Salicornia herbacea L.) powder on high-fat diet-induced obese rats
Mi Joung Kim, Hyun Young Jun and Jung Hee Kim
Department of Food and Nutrition, College of Natural Sciences, Seoul Women's University, Seoul 139-774, Korea.

To whom correspondence should be addressed. tel: +82-2-970-5646, Email: jheekim@swu.ac.kr
Received August 06, 2014; Revised September 04, 2014; Accepted February 27, 2015.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.


Abstract

Purpose

The objective of this study was to examine whether Hamcho freeze-dried powder and Hamcho freeze-dried nano powder have an anti-obese effect on high fat diet-induced obese rats.

Methods

Sprague Dawley rats were divided into 6 different groups, each of which was bred for 8 weeks with a different experimental diet: normal diet group (NC), high fat diet group (HFC), high fat diet + 2% Salicornia herbacea L. freeze-dried powder group (2% HS), high fat diet + 5% Salicornia herbacea L. freeze-dried powder group (5%HS), high fat diet + 1% Salicornia herbacea L. freeze-dried nano powder group (1% HSN), high fat diet + 2% Salicornia herbacea L. freeze-dried nano powder group (2% HSN).

Results

The 5% HS group showed a weight loss effect in body weight, liver and adipose tissue by reducing the amount of dietary intake and food efficiency ratio. In addition, the 5% HS group showed a significant reduction of serum leptin concentration, while having a beneficial effect on the improvement of lipid metabolism such as increase the serum concentration of adiponectin. However, Hamcho freeze-dried nano powder did not show a weight loss effect.

Conclusion

Overall data indicated that Hamcho seemed to have anti-obesity effects. In particular, consumption of 5% Hamcho freeze-dried powder might have beneficial effects on body weight, serum adiponectin level, and lipid profiles since it led to reduced body weight and growth of adipose tissues by suppressing dietary intakes. However conduct of further research studies is needed for analysis of active components and biochemical action mechanism of Hamcho.

Keywords: Salicornia herbacea L.; anti-obesity effect; lipid profile; leptin; adiponectin

Figures


 Fig. 1
Body weight change
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Tables


 Table 1
Composition of experimental diets (%)
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Table 2
Effect of Salicornia herbacea L. powder on final body weight, food intake and food efficiency ratio1)
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Table 3
Effect of Salicornia herbacea L. powder on liver weight, relative liver weight, epididymal white adipose tissue weight and relative epididymal white adipose tissue weight1)
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Table 4
Effect of Salicornia herbacea L. powder on feces weight, feces water and lipid contents1)
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Table 5
Effect of Salicornia herbacea L. powder on serum lipid profiles1)
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Table 6
Effect of Salicornia herbacea L. powder on liver triglyceride and total cholesterol contents and cytosolic fatty acid synthase level1)
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Table 7
Effect of Salicornia herbacea L. powder on serum leptin and adiponectin1)
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Notes

This study was supported by a R&D grant of Korea Institute of Planning & Evaluation for Technology in Food, Agriculture, Forestry & Fisheries (IPET 109147-3).

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