Abstract
Epilepsy surgery is classified into two types: curative epilepsy surgery and palliative surgery. The most frequently performed curative epilepsy surgery is an anterior temporal lobectomy with amygdalohippocampectomy (ATL with AH). ATL with AH includes the resection of epileptic hippocampus/amygdala and anterior temporal lobe (3~4cm from temporal pole) and is performed for treating drug refractory mesial temporal lobe epilepsy. A literature reports that more resection of epileptic hippocampus had a better surgical outcome. However, a surgery should be planned to prevent or minimize a postsurgical memory decline especially in resection of a dominant temporal lobe. Cortisectomy is a resection of localized epileptic focus in patients with neocortical epilepsy such as frontal, parietal, occipital, and lateral temporal lobe epilepsies. Most of neocortical epilepsy patients need an intracranial electrode implantation for determination of resection margin and a brain stimulation on intracranial electrodes for functional mapping. For a successful cortisectomy, an epilepsy surgery team should have a good amount of knowledge and experiences in intracranial EEG monitoring for intractable epilepsy patients. It is very important to place the intracranial electrodes at a brain region where epileptic focus is located because a wrong placement of intracranial electrodes results in failure of surgery. The surgical principles of functional hemispherectomy (FH) aim at disconnecting the hemisphere while leaving as much of the ipsilateral brain as possible intracranially; it has been characterized as anatomically subtotal but physiologically complete hemispherectomy. The original technique consists of a large central tissue removal, complete callosotomy, frontal and parieto-occipital disconnection, temporal lobectomy and insular corticectomy. The candidates of FH are drug refractory partial epilepsy patients who have unilateral epileptic focus and severe brain damage in ipsilateral hemisphere with loss of finger movements of contralateral hand. Corpus callosotomy is a surgical technique severing the corpus callosum so that communication between the cerebral hemispheres is interrupted. In contrast with lobectomy, corpus callosotomy does not involve removing any brain tissue. Instead, it usually involves cutting the front two-thirds of this bundle (anterior callosotomy). Sometimes the other one-third is cut later (complete callosotomy). Corpus callosotomy is most effective for atonic seizures ("drop attacks"), less effective for tonic-clonic seizures and tonic seizures. Additionally, multiple subpial transection and neuro-stimulation techniques are described.
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