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Abstract
Although symptoms related to airflow obstruction are the most prominent symptoms in patients with chronic obstructive pulmonary disease (COPD), there are many local and systemic complications contributing to the morbidity and mortality of the patients. This review article briefly discusses the following complications of COPD and their clinical implications: change of pulmonary circulation, peripheral edema, systemic inflammation, cardiovascular complication, weight loss, skeletal muscle dysfunction, osteoporosis, and anxiety. A better understanding and management of these complications as well as treatment of the airflow obstruction can improve the quality of life, and even the survival of the patients.
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References
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