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Choi: Genetic Test
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Journal of the Korean Medical Association

Journal of the Korean Medical Association 2003; 46(6): 521-526.

Published online: 30 June 2003

DOI: https://doi.org/10.5124/jkma.2003.46.6.521

Genetic Test

Jong Rak Choi, M.D.

Department of Laboratory Medicine, Yonsei University College of Medicine, Severance Hospital, Korea. cjr0606@yumc.yonsei.ac.kr

Copyright © 2003 Korean Medical Association

(open-access):

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The genetic test is a powerful diagnostic tool targeting DNA and RNA, now widely used not only in diagnosis of cancers, infectious disease, genetic disease, but also ABO genotyping, HLA typing, and forensic medicine. Even though a genetic test is of an important diagnostic value, the technical difficulty and expense make it difficult for it to completely replace the standard tests. As it is a test of high sensitivity, there is a possibility of misjudgment by errors in sample. Supplementary tests such as morphology analysis or tissue pathology may be helpful in such cases. The automation of molecular-genetic diagnostic methods such as PCR, DNA sequencing, and DNA chip will help genetic tests highlighted in laboratories in the near future.

Keywords: Genetic test, DNA, Molecular-genetic diagnostic methods

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