Journal List > Ann Clin Microbiol > v.20(3) > 1078575

Kim, Kim, and Kim: High Prevalence of Rotavirus G4P[6] Genotypes among Neonates in Two Korean Hospitals

Abstract

Background

The introduction of rotavirus vaccines has decreased the prevalence of rotavirus infections and might have changed the distribution of rotavirus genotypes. However, neonates are not eligible for vaccination and, therefore, are at risk for rotavirus infection while in the hospital nursery or neonatal intensive care unit. Our aim was to evaluate the shift of genotypes of group A rotavirus strains among neonates cared for in two geographically distant hospitals in Korea. between 2011 and 2013.

Results

Among the 63 tested neonates less than one month of age, 61 (96.8%) were infected with genotype G4P[6].

Conclusion

This study identified G4P[6] as the most frequently isolated genotypes among neonates in Korea; therefore, prevention of the G4P[6] genotype should be considered for neonates.

References

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Table 1.
The genotypic distributions of rotaviruses isolated from neonates less than one month of age in this study
Hospital, year, area No. of rotavirus genotyped specimens G4P[6](n) GxP[6]*(n) G4P[x]*(n) Non-G4P[6], GxP[6], G4P[x] (n) G4P[6], xP[6], Gx G4P[x](%)
Hangang Sacred Heart Hospital, 2011–2012, Seoul 27 25 0 0 2(G1P[6], G1P[x]) 92.6%
Busan Saint Mary Hospital, 2013 Busan 36 30 6 0 0 100%
Total 63 61 0 0 2 96.8%

*x indicated non-typed strain.

Table 2.
The distribution of rotaviruses isolated from neonates or children in Korea, confirming a high prevalence of G4P[6] genotype in neonates
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