Late Prosthetic Joint Infection and Bacteremia by Bacillus cereus Confirmed by 16S rRNA Sequencing and Hip Joint Tissue Pathology

Hyun Cheol Oh; Young Ah Kim; Jihye Ha; Yu Jin Park; Yee Jeong Kim; Hyun Cheol Oh; Young Ah Kim

doi:10.5145/ACM.2021.19.2.54

Journal List > Ann Clin Microbiol > v.19(2) > 1078556

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Oh, Kim, Ha, Park, Kim, Oh, and Kim: Late Prosthetic Joint Infection and Bacteremia by Bacillus cereus Confirmed by 16S rRNA Sequencing and Hip Joint Tissue Pathology

Original Article

Ann Clin Microbiol 2016;19(2):54-57.

Published online: 12 June 2016

DOI: https://doi.org/10.5145/ACM.2021.19.2.54

Late Prosthetic Joint Infection and Bacteremia by Bacillus cereus Confirmed by 16S rRNA Sequencing and Hip Joint Tissue Pathology

Hyun Cheol Oh³, Young Ah Kim⁴, Jihye Ha¹, Yu Jin Park¹, Yee Jeong Kim², Hyun Cheol Oh³, Young Ah Kim⁴

^¹Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul

^²Departments of Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea

^³Orthopedic Surgery, National Health Insurance Service Ilsan Hospital, Goyang, Korea

^⁴Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea

Correspondence: Young Ah Kim, Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, 100 Ilsan-ro, Ilsandong-gu, Goyang 10444, Korea. (Tel) 82-31-900-0908, (Fax) 82-31-900-0925, (E-mail) yakim@nhimc.or.kr

Received 3 May 2016 Revised 27 May 2016 Accepted 9 June 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Bacillus cereus is a widespread organism in nature and a member of the B. cereus group of catalase-positive, aerobic, spore-forming, Gram-positive bacilli. B. cereus found in blood is often dismissed as a contaminant in the absence of repeated isolation from multiple cultures. Soft tissue and bone infection due to B. cereus have been associated with trauma, intravenous drug use, and an immunocompromised state. We report a very late prosthetic joint infection of the hip joint and consequent bacteremia caused by B. cereus, which occurred 13 years after total hip replacement surgery in the absence of recent trauma or intervention.

Keywords: Arthritis, Bacillus cereus, Bacteremia, Prosthesis, 16S rRNA

References

1. Logan NA, Popovic T, Hoffmaster A. Bacillus and other aerobic endospore-forming bacteria. Murray PR, Baron EJ, Jorgensen JH, editors. Manual of Clinical Microbiology. Washington, DC: ASM Press;2007. p. 455.

2. Kuroki R, Kawakami K, Qin L, Kaji C, Watanabe K, Kimura Y, et al. Nosocomial bacteremia caused by biofilm-forming Bacillus cereus and Bacillus thuringiensis. Intern Med. 2009; 48:791–6.

3. Park JH, Jang AS, Han SW, Kim YC, Lee KR, Park SH, et al. A case of bacillus cereus infection with pneumonia and bacteremia.

4. Nicholson WL, Munakata N, Horneck G, Melosh HJ, Setlow P. Resistance of Bacillus endospores to extreme terrestrial and extraterrestrial environments. Microbiol Mol Biol Rev. 2000; 64:548–72.

5. Luna VA, King DS, Gulledge J, Cannons AC, Amuso PT, Cattani J. Susceptibility of Bacillus anthracis, Bacillus cereus, Bacillus mycoides, Bacillus pseudomycoides and Bacillus thuringiensis to 24 antimicrobials using sensititre automated microbroth dilution and Etest agar gradient diffusion methods. J Antimicrob Chemother. 2007; 60:555–67.

6. Noble RC and Reeves SA. Bacillus species pseudosepsis caused by contaminated commercial blood culture media. JAMA. 1974; 230:1002–4.

7. Curtis JR, Wing AJ, Coleman JC. Bacillus cereus bacteraemia. A complication of intermittent haemodialysis. Lancet. 1967; 1:136–8.

8. Akesson A, Hedström SA, Ripa T. Bacillus cereus: a significant pathogen in postoperative and posttraumatic wounds on orthopaedic wards. Scand J Infect Dis. 1991; 23:71–7.

9. Lamagni T. Epidemiology and burden of prosthetic joint infections. J Antimicrob Chemother. 2014; 69(Suppl 1):i5–10.

10. Lindsay D, Brözel VS, Von Holy A. Biofilm-spore response in Bacillus cereus and Bacillus subtilis during nutrient limitation. J Food Prot. 2006; 69:1168–72.

11. Costerton JW. Biofilm theory can guide the treatment of device-related orthopaedic infections. Clin Orthop Relat Res. 2005. 7–11.

12. Peel TN, Cheng AC, Buising KL, Choong PF. Microbiological aetiology, epidemiology, and clinical profile of prosthetic joint infections: are current antibiotic prophylaxis guidelines effective? Antimirob Angents Chemother. 2012; 56:2386–91.

13. Dubouix A, Bonnet E, Alvarez M, Bensafi H, Archambaud M, Chaminade B, et al. Bacillus cereus infections in traumatology-orthopaedics department: retrospective investigation and improvement of healthcare practices. J Infect. 2005; 50:22–30.

14. Gallo PH, Melton-Kreft R, Nistico L, Sotereanos NG, Sewecke JJ, Stoodley P, et al. Demonstration of Bacillus cereus in orthopaedic-implant-related infection with use of a multi-primer polymerase chain reaction-mass spectrometric assay: report of two cases. J Bone Joint Surg Am. 2011; 93:e85.

15. Kim MJ, Chang BH, Kim IC, Lee DW, Ahn M. Posttraumatic Bacillus cereus endophthalmitis. J Korean Ophthalmol Soc. 2005; 46:1597–604.

Fig. 1.

Polymorphonuclear leukocytes and nuclear debris with fibrinous exudate (Hematoxylin-esoin stain, ×400).

Fig. 2.

Clustered Gram-positive bacilli in fibrinous exudate (Gram stain, ×400, ×1,000).

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