Journal List > Ann Clin Microbiol > v.18(4) > 1078528

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Lee, Kang, Huh, Ki, and Lee: First Report of Yokenella regensburgei Isolated from the Wound Exudate after Disarticulation Due to Diabetic Foot Infection in Korea
Original Article

Ann Clin Microbiol 2015;18(4):135-139.

Published online: 5 December 2015

DOI: https://doi.org/10.5145/ACM.2015.18.4.135

First Report of Yokenella regensburgei Isolated from the Wound Exudate after Disarticulation Due to Diabetic Foot Infection in Korea

Sae-Mi Lee, Young-Jin Kang, Hee Jae Huh, Chang-Seok Ki, Nam Yong Lee

Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Correspondence: Hee Jae Huh, Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea. (Tel) 82-2-3410-1836, (Fax) 82-2-3410-2719, (E-mail) heejae.huh@samsung.com

Received 6 August 201530 November 2015       Accepted 1 December 2015

Copyright © 2015 The Korean Society of Clinical Microbiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

초록

Yokenella regensburgei, a member of the family Enterobacteriaceae, is rarely isolated in humans. Here, we report a 71-year-old man with diabetic foot infection from which Y. regensburgei was isolated. Follow-ing debridement and disarticulation of the foot, an exudate specimen was obtained, from which Gram- negative bacilli were recovered. The organism was identified as Y. regensburgei using the Vitek 2 system (bioMérieux, USA) and 16S rRNA and gyrB gene sequencing. To our knowledge, this is the first case of Y. regensburgei isolation in Korea.

Keywords: Diabetic foot, DNA sequencing, Yokenella regensburgei

REFERENCES

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crossref
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Fig. 1.
(A) Gram stain microscopy of a colony grown on a blood agar plate. Gram-negative rods are shown (Gram stain, ×1,000). (B) Small, grayish, mucoid colonies on a blood agar plate, 2 days. (C) Small, colorless, mucoid colonies on a MacConkey agar plate, 2 days.
acm-18-135f1.tif
Table 1.
Reports of Yokenella regensburgei isolation in clinical specimens
Year Age/Sex x Clinical diagnosis Specimen Underlying condition Treatment Outcome
1994 [3] 74/M Septic arthritis Knee wound Alcohol abuse AMK Unknown
1994 [3] 35/F Transient bacteremia Blood Alcohol abuse, liver disease, pancreatitis CIP Improved
2005 [9] 82/M Perimalleolar ulcer Wound Chronic kidney disease, venous thrombosis CIP (oral) Improved
2009 [10] 77/M Septic shock, abdominal abscess, pneumonia Blood, abdominal aspirate, sputum DM, esophageal adenocarcinoma, renal cancer P/T, LVF Transferred, no follow-up
2011 [11] 42/M Soft tissue infection with bacteremia Blood DM, steroids, immunosuppressants CTR Improved
2013 [12] 48/M Cellulitis Blood, bulla aspirate Multiple myeloma, autologous stem cell transplant, liver failure, chronic kidney disease, steroids IPM/CS, CLI, GEN Died
2013 [13] 5/M Enteric fever Blood None CIP Improved
This case 71/M Diabetic foot infection Wound DM, chronic kidney disease P/T below-knee amputation Improved

Abbreviations: DM, diabetes mellitus; AMK, amikacin; CIP, ciprofloxacin; P/T, piperacillin/tazobactam; LVF, levofloxacin; CTR, ceftriaxone; IPM/CS, mipenem/cilastatin; CLI, clindamycin; GEN, gentamicin.

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