Possibility of Frequent Detection of Invasive Cyberlindera fabianii Infection Using Molecular Method

Young Jin Kim; John Jeongseok Yang; Hee Joo Lee

doi:10.5145/ACM.2015.18.4.133

Journal List > Ann Clin Microbiol > v.18(4) > 1078527

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Kim, Yang, and Lee: Possibility of Frequent Detection of Invasive Cyberlindera fabianii Infection Using Molecular Method

Original Article

Ann Clin Microbiol 2015;18(4):133-134.

Published online: 5 December 2015

DOI: https://doi.org/10.5145/ACM.2015.18.4.133

Possibility of Frequent Detection of Invasive Cyberlindera fabianii Infection Using Molecular Method

Young Jin Kim, John Jeongseok Yang, Hee Joo Lee

Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul, Korea

Correspondence: Hee Joo Lee, Department of Laboratory Medicine, Kyung Hee University Hospital, School of Medicine, Kyung Hee University, 23 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, Korea. (Tel) 82-2-958-8672, (Fax) 82-2-958-8609, (E-mail) leehejo@khmc.or.kr

Received 23 November 20154 December 2015 Accepted 7 December 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

초록

A case of fungemia caused by Cyberlindera fabianii was reported in the September issue of Annals of Clinical Microbiology. The C. fabianii that causes rare invasive infection can easily be misidentified as Candida utilis by Vitek-2 YST ID (bioMérieux, USA) and as Candida pelliculosa by API kit (bioMérieux, USA) with high probability. Recently, we also experienced a case of fungemia caused by C. fabianii that was misidentified as C. pelliculosa using API 20C Aux (bioMérieux, USA). As molecular identification is be-coming more widespread, cases of C. fabianii infection are expected to be more frequently identified.

Keywords: Cyberlindera fabianii, Molecular biology species

REFERENCES

1.Lee JI., Yu S., Park JS., Joo EJ., Shin JH., Kwon MJ. Successful treatment of fungemia caused by Cyberlindnera fabianii with anidulafungin: a case report. Ann Clin Microbiol. 2015. 18:94–7.

2.Jindal N., Dhuria N., Arora S., Arora D. Cyberlindnera ( Pichia) fabianii infection in a neutropenic child: importance of molecular identification. JMM Case Rep. 2015. doi: 0.1099/jmmcr.0.000033.

3.Hamal P., Ostransky J., Dendis M., Horváth R., Ruzicka F., Buchta V, et al. A case of endocarditis caused by the yeast Pichia fabianii with biofilm production and developed in vitro resistance to azoles in the course of antifungal treatment. Med Mycol. 2008. 46:601–5.

4.Wu Y., Wang J., Li W., Jia H., Che J., Lu J, et al. Pichia fabianii blood infection in a premature infant in China: case report. BMC Res Notes. 2013. 6:77.

5.Won EJ., Shin JH., Lee WK., Koo SH., Kim SY., Park YJ, et al. Distribution of yeast and mold species isolated from clinical specimens at 12 hospitals in Korea during 2011. Ann Clin Microbiol. 2013. 16:92–100.

6.Mlinarić-Missoni E., Vágvölgyi C., Kocsubé S., Hatvani L., Škarić I., Lukić-Grlić A. Cyberlindnera fabianii in the neonatal and pae-diatric intensive care unit: case reports. JMM Case Rep. 2015. doi: 10.1099/jmmcr.0.000032.

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