Journal List > J Korean Soc Spine Surg > v.18(1) > 1075932

Park, Lee, Kim, and Kim: Effect of the Corrective Osteotomy in Ankylosing Spondylitis to Quality of Life(QOL)

Abstract

Study Design

This is retrospective study.

Objective

We evaluated the radiologic changes and quality of life after corrective osteotomy in kyphotic deformity of ankylosing spondylitis.

Summary of Literature Review

There is few study about that relationship between corrective osteotomy and quality of life.

Materials and Methods

Retrospective study about 16 patients who underwent corrective osteotomy from 2005 September to 2007 December was done. Radiologic assessments of sagittal balance were performed on the criteria of thoracic kyphosis, lumbar lordosis, distance between the vertical line on midpoint of C7 and posterosuperior point of S1 pre and postoperatively. Disease specific instruments: the Bath ankylosing spondylitis disease activity index (BASDAI) and the Bath ankylosing spondylitis functional index (BASFI) were applied. Clinical assessments were performed with short form-36 through interview and telephone.

Results

The mean thoracic kyphosis was changed from 46.1 degrees to 39.3 degrees. The mean lumbar lordosis was corrected from - 7.4 degrees to - 38.4 degrees, and the mean distance between vertical lines of C7 and S1 was improved from 127.1mm to 30mm. There were significant changes in the subgroup of Physical function, Role physical, Vitality, Social function, Role emotional, Mental health. (p<0.05) The changes of BASDAI, BASFI, Bodily pain and General health were not significant. And similar improvements in the radiological results and SF-36 scores were in the 6 patients with Andersson lesion.

Conclusion

The parameters of radiographic assessment were improved after corrective osteotomy in the fixed kyphotic deformity of ankylosing spondylitis. General function, social function and mental health were also improved.

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Figures and Tables%

Fig 1.
Significant improvements were seen 6 categories (physical function, role physical, vitality, social function, role emotional, mental health) after corrective osteotomy(p-value<0.05). There were also improvements in bodily pain and general health, but those were not significant (p-value=0.263, p-value=0.314).
jkss-18-13f1.tif
Fig 2.
Improvement in mental component summary was better than that in physical component summary (p-value<0.05).
jkss-18-13f2.tif
Table 1.
Demographic data
Ankylosing spondylitis(N=16)
Age 36.5 years (30~67)
Sex Male : Female = 13 : 3
Followup period 26.7 months(24~30)
Andersson lesion 6 cases (5 males, 1 male)
Surgical technique
Pedicle subtraction osteotomy 16 cases
L1, L2, L3 (4, 3, 9)
Smith-Petersen osteotomy 5 cases
T9 – T10 1 case
T10 – T11 1 case
T12 – L1 3 cases
Anterior corpectomy & anterior interbody fusion 6 cases
Table 2.
Radiologic results after corrective osteotomy
Preoperative Postoperative
Thoracic kyphosis(°) 46.1(28~70) 39.3(20~59)
Lumbar lordosis(°) -7.4(-12~0) -38.4(-51~-31)
Distance between C7 plumb line and S1 127.1(59~203) 30.0(0~55)
Table 3.
The Bath ankylosing spinal functional index and the Bath ankylosing spondylitis disease activity index†† were not changed significantly after corrective osteotomy.
Preoperative Postoperative P-value
BASFI 6.0±1.9 5.0±1.0 0.45
BASDAI†† 5.9±2.0 4.8±2.1 0.53
Table 4.
There were not significant change between the groups of patients with thoracic kyphotic deformity and Andersson lesion and the groups of patients with thoracic kyphotic deformity in radiologic parameters (*p-value=0.36, **p-value=0.14, ***p-value=0.62).
Thoracic kyphotic deformity with Andersson lesion (N=6) Thoracic kyphotic deformity without Andersson lesion (N=10)
Thoracic kyphosis(°)* 49.1(30~69) 42.3(25~57) 45.2(28~70) 38.9(20~59)
Lumbar lordosis(°)** -8.8(-12~-5) -39(-51~-32) -7.1(-11~0) -39.2(-44~-31)
Distance between C7 plumb line and S1(mm)*** 120.8(54~184) 29.6(0~41) 134.2(81~203) 34.2(15~85)
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