Two Cases of Bacteremia Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus

Jung Hyun Kim; Eun Jung Kang; Yun Seok Jung; Min Hyeok Jeon; Tae Hyeong Kim; Hue Bong Sin; Su Jin Park; Eun Ju Choo

doi:10.3947/ic.2009.41.1.58

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Kim, Kang, Jung, Jeon, Kim, Sin, Park, and Choo: Two Cases of Bacteremia Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus

Case Report

Infection and Chemotherapy

Infection and Chemotherapy 2009; 41(1): 58-61.

Published online: 28 February 2009

DOI: https://doi.org/10.3947/ic.2009.41.1.58

Two Cases of Bacteremia Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus

Jung Hyun Kim, M.D.¹, Eun Jung Kang, M.D.¹, Yun Seok Jung, M.D.¹, Min Hyeok Jeon, M.D.¹, Tae Hyeong Kim, M.D.¹, Hue Bong Sin, M.D.², Su Jin Park³, Eun Ju Choo, M.D.¹

¹Department of Internal Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea.

²Department of Laboratory Medicine, Soonchunhyang University School of Medicine, Bucheon, Korea.

³Center for Antimicrobial Resistance and Microbial Genetics, University of Ulsan, Seoul, Korea.

Correspondence: Eun Ju Choo, M.D. Department of Internal Medicine, Soonchunhyang University School of Medicine, 1174 Jung-Dong, Wonmi-Gu, Bucheon 420-767, Korea. Tel: +82-32-621-5202, Fax: +82-32-621-5016, mdchoo@schbc.ac.kr

Received 2 October 2008 Accepted 9 December 2008

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Recent reports have described an increasing incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in patients who do not exhibit established risk factors for healthcare exposure. We report two cases of CA-MRSA bacteremia complicated by vertebral osteomyelitis. Both of CA-MRSA isolates were resistant to beta-lactam agents, but susceptible to clindamycin, trimethoprim-sulfamethoxazole, gentamicin, ciprofloxacin, and tetracycline. Both isolates carried staphylococcal cassette chromosome mec (SCCmec) type IVA, and were identified as sequence type (ST) 72 by mlultilocus sequence typing (MLST). However, the Panton-Valentine leukocidin (PVL) gene was not identified.

Keywords: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), Bacteremia

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