Abstract
Although Staphylococcus epidermidis is a frequent cause of prosthetic valve endocarditis (PVE), it is regarded as a rare pathogen of native valve endocarditis (NVE). We report a case of NVE caused by methicillin-resistant S. epidermidis in a 62-year-old man. The bacterium was isolated from blood and tissue culture. The patient underwent valve replacement due to heart failure and was successfully treated by surgery and vancomycin administration for 7 weeks.
References
1. Chu VH, Woods CW, Miro JM, Hoen B, Cabell CH, Pappas PA, Federspiel J, Athan E, Stryjewski ME, Nacinovich F, Marco F, Levine DP, Elliott TS, Fortes CQ, Tornos P, Gordon DL, Utili R, Delahaye F, Corey GR, Fowler VG Jr. International Collaboration on Endocarditis-Prospective Cohort Study Group. Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis. Clin Infect Dis. 2008. 46:232–242.
2. Rogers KL, Fey PD, Rupp ME. Coagulase-negative staphylococcal infections. Infect Dis Clin N Am. 2009. 23:73–98.
3. Abelsi I, Rekik S, Znazen A, Maaloul I, Abid D, Maalej A, Kharrat I, Ben Jemaa M, Hammemi A, Kammoun S. Native valve infective endocarditis in a tertiary care center in a developing country (Tunisia). Am J Cardiol. 2008. 102:1247–1251.
4. Lee CH, Tsai WC, Liu PY, Tsai LM, Ho MT, Chen JH, Lin LJ. Epidemiologic features of infective endocarditis in Taiwanese adults involving native valves. Am J Cardiol. 2007. 100:1282–1285.
5. Son JS, Ki HK, Oh WS, Peck KR, Lee NY, Park KH, Park PW, Song JH. Observation of clinical characteristics of infective endocarditis. Infect Chemother. 2005. 37:152–160.
6. Chu VH, Cabell CH, Abrutyn E, Corey GR, Hoen B, Miro JM, Olaison L, Stryjewski ME, Pappas P, Anstrom KJ, Eykyn S, Habib G, Benito N, Fowler VG Jr. International Collaboration on Endocarditis Merged Database Study Group. Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the international collaboration on endocarditis merged database. Clin Infect Dis. 2004. 39:1527–1530.
7. Vuong C, Otto M. Staphylococcus epidermidis infections. Microbes Infect. 2002. 4:481–489.
8. Ziebuhr W, Hennig S, Eckart M, Kränzler H, Batzilla C, Kozitskaya S. Nosocomial infections by Staphylococcus epidermidis: how a commensal bacterium turns into a pathogen. Int J Antimicrob Agents. 2006. 28:Suppl 1. S14–S20.
9. Beekmann SE, Diekema DJ, Doern GV. Determining the clinical significance of coagulase-negative staphylococci isolated from blood cultures. Infect Control Hosp Epidemiol. 2005. 26:559–566.
10. Tokars JI. Predictive value of blood cultures positive for coagulase-negative staphylococci: implications for patient care and health care quality assurance. Clin Infect Dis. 2004. 39:333–341.