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Moon Han Choi, M.D., Eun Ju Choo, M.D., Tae Hyong Kim, M.D.
, Min Hyok Jeon, M.D., Eui Ju Park, M.D., Dong Won Shin, M.D., Sul Hee Yi, M.D., Jong Hyo Choi, M.D.
, Min Hyok Jeon, M.D., Eui Ju Park, M.D., Dong Won Shin, M.D., Sul Hee Yi, M.D., Jong Hyo Choi, M.D.
Abstract
Dengue virus infection is an emerging imported disease in Korea. A total of 4 cases of dengue fever or dengue hemorrhagic fever diagnosed at Soonchunhyang University Hospital in Bucheon between January 2001 and December 2007 were retrospectively reviewed. In addition, relevant domestic literatures from Korean bibliographic databases, which matched 'dengue fever', 'dengue hemorrhagic fever' or 'dengue shock syndrome' as key words, have been reviewed. Ten articles (13 patients) met the inclusion criteria and were included in this review. All the patients except for one, who was infected in Africa, were infected in Asian countries: Philippines (4), Indonesia (3), India (2), Cambodia (2), Sri Lanka (1), Thailand (1), Bangladesh (1), Myanmar (1), and Malaysia (1). Clinical manifestations after returning from abroad were as follows: fever (100%), chills (82%), headache (65%), myalgia (53%), nausea (41%), neutropenia (82%), thrombocytopenia (82%), and elevation of AST (82%) and ALT (53%). Most of the patients improved with conservative care except for one who died of dengue shock syndrome.
Figures and Tables
Figure 1
Average annual number of cases of dengue or severe dengue fever reported to WHO and average annual number of countries reporting dengue (16) World Health Organization. DengueNet avail from:(http://www.who.int/denguenet).
Table
Characteristics of the Patients with Dengue Fever (n=17)
*our cases
†Incubation period is the amount of time between infection on return from abroad to the start of symptoms. Blank cells means that do not know.
‡CBC : complete blood count, WBC : white blood cell, PLT : platelet, ↑/↓ : above/below the normal range (WBC : 4,500-11,000/mm3, PLT : 150,000-350,000/mm3)
§LFT : liver function test, AST : aspartic acid transaminase, ALT : alanine transaminase, ↑/↓ : above/below the normal range (AST/ALT : 0-35 IU/L), - : not mentioned
∥ELISA : enzyme-linked immunosorbent assay
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