A Case of Diabetic Foot Infection due to Mycobacterium mageritense

Chung-Jong Kim; Nak-Hyun Kim; Moonsuk Kim; Kye-Hyung Kim; Jae Hyun Jeon; Moon Seok Park; Kyoung Un Park; Wan Beom Park; Sang-Won Park; Hong Bin Kim; Nam Joong Kim; Myoung-don Oh; Kang Won Choe

doi:10.3947/ic.2008.40.6.337

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Kim, Kim, Kim, Kim, Jeon, Park, Park, Park, Park, Kim, Kim, Oh, and Choe: A Case of Diabetic Foot Infection due to Mycobacterium mageritense

Case Report

Infection and Chemotherapy

Infection and Chemotherapy 2008; 40(6): 337-340.

Published online: 31 December 2008

DOI: https://doi.org/10.3947/ic.2008.40.6.337

A Case of Diabetic Foot Infection due to Mycobacterium mageritense

Chung-Jong Kim, M.D.¹, Nak-Hyun Kim, M.D.¹, Moonsuk Kim, M.D.¹, Kye-Hyung Kim, M.D.¹, Jae Hyun Jeon, M.D.¹, Moon Seok Park, M.D.², Kyoung Un Park, M.D.³, Wan Beom Park, M.D.¹, Sang-Won Park, M.D.¹, Hong Bin Kim, M.D.¹, Nam Joong Kim, M.D.¹, Myoung-don Oh, M.D.¹, Kang Won Choe, M.D.¹

¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

²Department of Orthopedic Surgery, Seoul National University College of Medicine, Seoul, Korea.

³Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.

Correspondence: Hong Bin Kim, M.D. Department of Internal Medicine, Seoul National University College of Medicine, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggido 463-707, Korea. Tel: +82-31-787-7021, Fax: +82-31-787-4052, hbkimmd@snu.ac.kr

Received 4 July 2008 Accepted 13 August 2008

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Diabetic foot infection is one of the important complications in patients with advanced diabetes mellitus. Limb threatening infections such as osteomyelitis, abscess, and necrotizing fasciitis are frequently accompanied by the disease. Non-tuberculous mycobacterium (NTM) is a rare causative organism of diabetic foot infection. Thus, if one is not suspicious or meticulous, infection due to NTM will be easily overlooked and this will result in delayed diagnose and treat. Therefore, it is necessary to consider NTM as the causative organism if the wound does not respond to the conventional antibiotic treatment and the culture from the adequately obtained specimen reveals atypical acid-fast bacilli. We present a case of diabetic foot infection with osteomyelitis and abscess due to Mycobacterium mageritense, one of the rapid growing mycobacteria, that was successfully treated with surgical debridement and appropriate antibiotic treatment.

Keywords: Mycobacterium mageritense, Diabetic foot, Osteomyelitis

Figures and Tables

Figure 1

(A) 3.5 cm-sized large ulcerative lesion was found on the lateral aspect of left malleolus. (B) The diffuse abnormal signal intensity of the bone marrow with intramedullary rim enhancement, suggestive of osteomyelitis with abscess in left malleolus, was shown on the coronal view of T1-weighted magnetic resonance image.

Figure 2

Eugonic and smooth colonies were visible on blood agar plate after 3-day incubation at 37℃.

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