A Case of Cryptococcal Osteomyelitis with Paraspinal Abscess

Ryan Oh; Eun Hee Song; Ki Ho Park; Oh Hyun Cho; Tark Kim; Gui Jun Yun; Byeong Seok Sohn; Heungsup Sung; Mi-Na Kim; Yang Soo Kim; Jun Hee Woo

doi:10.3947/ic.2008.40.5.284

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Oh, Song, Park, Cho, Kim, Yun, Sohn, Sung, Kim, Kim, and Woo: A Case of Cryptococcal Osteomyelitis with Paraspinal Abscess

Case Report

Infection and Chemotherapy

Infection and Chemotherapy 2008; 40(5): 284-287.

Published online: 25 October 2008

DOI: https://doi.org/10.3947/ic.2008.40.5.284

A Case of Cryptococcal Osteomyelitis with Paraspinal Abscess

Ryan Oh, M.D.¹, Eun Hee Song, M.D.¹, Ki Ho Park, M.D.¹, Oh Hyun Cho, M.D.¹, Tark Kim, M.D.¹, Gui Jun Yun, M.D.¹, Byeong Seok Sohn, M.D.¹, Heungsup Sung, M.D.², Mi-Na Kim, M.D.², Yang Soo Kim, M.D.¹, Jun Hee Woo, M.D.¹

¹Department of Infectious Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

²Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Correspondence: Jun Hee Woo, M.D. Department of Infectious disease, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Punganp2-dong, Songpa-gu, Seoul 138-736, Korea. Tel: +82-2-3010-3802, Fax: +82-2-3010-6970, junheewoo@amc.seoul.kr

Received 23 June 2008 Accepted 8 September 2008

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Cryptococcosis is a disseminated infection caused by Cryptococcus neoformans. It usually causes pulmonary infection and meningitis in immunocompromised patients. However, osteomyelitis due to C. neoformans is extremely rare. It is generally known that cryptococcal osteomyelitis is a complication of disseminated cryptococcosis, appearing in 5-10%. We experienced a case of cryptococcal osteomyelitis with paraspinal abscess in a liver transplant patient.

Keywords: Cryptococcus neoformans, Cryptococcal Osteomyelitis, Paraspinal Abscess

Figures and Tables

Figure 1

(A) Initial magnetic resonance imaging shows a paraspinal abscess (arrow) and destruction of iliac bone (arrowhead). It involves erector spine muscle and iliac muscle. (B) Magnetic resonance imaging 4 weeks after the treatment shows decreased size of abscess.

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