Journal List > J Korean Soc Echocardiogr > v.4(1) > 1075230

Kang, Choue, Kim, Kim, Song, and Bae: Usefulness of Dobutamine Stress Echocardiography for Assessment of Cardiac Risk before Noncardiac Surgery

Abstract

Background

Two-dimensional echocardiography performed during incremental infusion of dobutamine has been shown to be a safe and accurate method for detection of coronary artery disease in patients who are unable to undergo conventional exercise testing. A significant proportion of these patients are referred for evaluation before undergoing noncardiac surgery.

Method

To assess the value of dobutamine stress echocardiography (DSE), for assessment of preoperative cardiac risk, 88 patients (male: 32, female: 56, mean age: 60 years) were evaluated. Patients records were reviewed to determine the short-term outcome of surgery. Significant cardiac events were defined as unstable angina, myocardial infarction and sudden cardiac death occurred before discharge. Intravenous dobutamine was infused in a graded fashion (10 to 45μg/kg/min in 3 minutes stages), with two-dimensional echocardiographic monitoring of segmental wall motion of left ventricle.

Results

1) The major reasons underwent dobutamine stress echocardiography were abnormalities of ECG such as ST-T changes, abnormal Q wave (65%: 64 of 98 patients) and history of coronary artery disease (29%: 28 of 98 patients).
2) Of the 88 patients who underwent noncardiac surgery, 85 (97%) patients were negative response in dobutamine stress echocardiography, and no patients had cardiac events, also 3 (3%) patients who had positve response did not occur cardiac events.
3) No major adverse effects occurred with stress test in any patient.

Conclusion

These results suggest that DSE is useful preoperative diagnostic method for predicting short-term surgical outcome in patients with suspicious coronary artery disease undergoing noncardiac surgery.

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Table 1.
Reasons of dobutamine stress echo(n = 98)
ECG abnormality  
Complete RBBB 1
ST-T changes 57
Abnormal Q-wave 7
Arrhythmias 5
Angina pectoris 25
Previous MI 3

MI: myocardial infarction

Table 2.
Causes of surgical procedures(n = 88)
Bone fracture 22
Arthritis 14
HIVD 13
GB and CBD stone 9
Cancer 8
Arterosclerosis obliterans 4
Acute appendicitis 3
Avascular necrosis 3
Uterine prolapse 3
Chronic otitis media 2
Others 7
Table 3.
Hemodynamic changes during dobutamine stress echocadiography
  Baseline Peak
Heart rate(beasts/min) 69 ± 12 122 ± 13
Systolic BP(mmHg) 129 ± 21 158 ± 33
Double product(×103) 8.5 ± 2.1 20.9 ± 7

: p < 0.001 vs. baseline

Mean dobutamine dosage: 39 ± 7μg/kg/min

Table 4.
Flow sheet of cardiac events
jkse-4-22f1.tif
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