Abstract
Background
Left Ventricular Hypertrophy(LVH) is well known independent predictors of cardiovascular morbidity and mortality. Recently echocardiography is popular method to measure Left Ventricular Mass(LVM) and detect LVH. The purpose of this study is to determine the mean values of LVM and criteria for LVH in Korean.
Methods
Two hundred and fifty five subjects who participate in the health clinic were selected and studied(among them, 47 subjects were excluded according to exclusion criteria). History, physical examination, routine laboratories, and echocardiography were performed to all of the subjects.
Results
The mean values of LVM, LVM corrected for body surface area(BSA). and LVM corrected for height are respectively: 199g, 114g/m2, and 119g/m in 119 Korean men. and 168g, 107g/m2, and 108g/m in 89 women, by echocardiography in accordance with the American Society of Echocardiography(ASE) convention. The criteria for LVH, based on mean plus two standard deviation for LVM. LVM/BSA, and LVM/height are, respectively: 301g, 168g/m2, and 181g/m in men, and 262g 165g/m2, and 168g/m in women.
Conclusions
The prevalence of LV hypertrophy in the entire study group using LV mass/surface criteria and LV mass/height are respectively 7.6% in men and 10.9% in women and 6.9% in men and 10% in women. There are little difference of the prevalance rate of LV Hypertrophy by whichever criteria were used, either based on LVM/body surface area or LVM/height while still correcting for body size.
References
1). Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. Circulation. 1977; 55:613–618.
2). Devereux RB, Lutas EM, Casale PN, Kligfield P, Eisenberg RR, Hammond IW, Miller DH, Reis G, Alderman MH, Laragh JH. Standardization of M-Mode echocardiographic left ventricular antomic measurements. JACC. 1984; 4:1222–1230.
3). Kannel WB, Cobb J. Left ventricular hypertrophy and mortality-results from the Framingham Study. Cardiology. 1992; 81(4–5):291–298.
4). Casale PN, Devereux RB, Milner M, Zullo G, Harshfield GA, Pickering TG, Laragh JH. Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. Ann Intern Med. 1986; 105:173–178.
5). Levy KM, Garrison RJ, Savage DD, Kannel WB, Castelli WP. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. J Engl J Med. 1990; 322:1561–1566.
6). Savage DD, Drayer JIM, Henry WL, Mathews EC, Ware JH, Gardin JM, Cohen ER, Epstein SE, Laragh JH. Echocardiographic assessment of cardiac anatomy and function in hypertensive subjects. Circulation. 1979; 59:623–632.
7). Reicheck N, Devereux RB. Left ventricular hypertrophy: relationship of antomic, echocardiographic and electrocardiographic findings. Circulation. 1981; 64:1391–1398.
8). Levy D, Savage DD, Garrison RJ, Anderson KM, Kannel WB, Castelli WP. Echocariographic criteria for left ventricular hypertrophy: The Framingham Heart Study Am J Cardiol. 1987; 59:956–960.
9). Dubois D, Dubois EF. A formula to estimate the approximate surface area if height and weight be known. Arch Intern Med. 1916; 17:863–871.
10). Feigenbaum H. Echocardiography. 3rd ed.Philadelphia: Lea & Febiger;1981. p. 51–118.
11). Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations reganding quantitatim in M-Mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978; 58:1072–1083.