Journal List > J Korean Soc Echocardiogr > v.2(2) > 1075164

Lee, Lee, Shon, Kang, Choe, Kim, Kim, Song, and Bae: Doppler Assessment of Mitral and Aortic flow in Exercise Stress Echocardiography

Abstract

Background

The pattern of left ventricular filling as depicted by Doppler echocardiographic transmitral flow velocities has been used to left ventricular diastolic properties and altered transmitral and aortic flow by abnormal myocardial wall motion and left ventricular function in ischemic heart disease was predicted during exercise stress echocardiography.

Methods

To determine the effects of altered wall motion on Doppler indexes of mitral and aortic flow, we studied 46 angina pectoris patients and divided into 3 groups(Group I: No wall motion abnormality before and after exercise. Group IIA: Wall motion abnormality after exercise and E/A ratio<1 at rest Group IIB: Wall motion abnormality after exercise and E/A ratio>1 at rest). Transmitral flow measurements comprised peak and integrated early passive(E) and late atrial(A) filling velocities and ratio. Aortic flow measurements comprised peak velocity and acceleration time.

Results

Heart rate in group I was 63.1/min at rest and 88.6/min at Doppler echocardiography after exercise. Group IIB was 63.6/min. 83.9/min, respectively. In group IIB E/A ratio was significantly decreased after exercise(p<0.001) and acceleration time of aortic flow was not significantly decreased.

Conclusion

Doppler echocardiographic transmitral aortic flow was altered by abnormal regional wall motion in ischemic heart disease during exercise stress echocardiography.

References

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Fig. 1.
Classification of subjects by treadmill exercise echocardiography.
WMA: wall motion abnormality
jkse-2-136f1.tif
Fig. 2.
Comparison of mitral flow in group I and IIB.
jkse-2-136f2.tif
Fig. 3.
Comparison of aortic flow in Group I and Group IIB.
jkse-2-136f3.tif
Table 1.
Doppler data of group l(n = 23)
Variables Before After P-value
Mitral flow      
HR (beat/min) 63.1 88.6 < 0.001
Peak E (cm/s) 74.4 88.6 0.0027
Peak A (cm/s) 59.1 83.9 < 0.001
E/A ratio 1.34 1.14 0.140
Ei (cm) 12.4 12.2 0.820
Ai (cm) 6.8 7.8 0.140
Ei / Ai 1.8 1.7 0.210
AT of E (msec) 79.7 69.7 0.048
Aortic flow      
Peak velocity (cm/s) 117.6 152.6 < 0.001
TVI (cm) 25.2 24.9 0.920
AT (msec) 67.2 48.9 0.005
Table 2.
Doppler data of group IIA(n = 8)
Variables Before After P-value
Mitral flow      
HR (beat/min) 70.4 84.6 0.099
Peak E (cm/s) 74.5 88.8 0.092
Peak A (cm/s) 84.5 98.3 0.310
E/A ratio 0.89 0.96 0.510
Ei (cm) 10.3 11.8 0.330
Ai (cm) 8.38 8.87 0.670
Ei / Ai 1.3 1.4 0.480
AT of E (msec) 66.5 71.6 0.650
Aortic flow      
Peak velocity (cm/s) 113.1 120.1 0.450
TVI (cm) 19.6 21.3 0.480
AT (msec) 75.5 58.3 0.120
Table 3.
Doppler data of group IIB(n = 15)
Variables Before After P-value
Mitral flow      
HR (beat/min) 63.6 83.9 < 0.001
Peak E (cm/s) 78.8 91.8 0.029
Peak A (cm/s) 61.4 89.3 < 0.001
E/A ratio 1.29 1.03 < 0.001
Ei (cm) 11.7 12.5 0.450
Ai (cm) 6.3 8.3 0.018
Ei / Ai 1.87 1.57 0.063
AT of E (msec) 83.0 81.5 0.830
Aortic flow      
Peak velocity (cm/s) 111.9 131.4 0.019
TVI (cm) 22.3 23.8 0.370
AT (msec) 68.8 66.7 0.770
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