Abstract
Figures and Tables
![]() | FIG. 1Effects of glutinous rice extract (GRE) on the formation of gastric lesions induced by ethanol (A), indomethacin (B), and water-immersion restraint stress (C) in rats. The indicated doses of GRE were administered to rats 30 min before ulcerogenic treatments. Each column represents the mean±SE (N=8). *p<0.05, †p<0.01 compared with the control (zero) group. |
![]() | FIG. 2Effects of glutinous rice extract (GRE) on the gastric mucin content (A and B) and gastric mucosal nonprotein sulfhydryl (NP-SH) concentration (C) in rats. (A) Change in the total gastric mucin content by GRE treatment. One hour after the indicated doses of GRE were administered to rats, the gastric mucin content was determined (N=3). *p<0.05 compared with the control (zero) group. (B) Changes in the gastric mucus content by GRE and ethanol treatments. Rats were pretreated with the indicated doses of GRE, and 30 min later, they were treated with 4 mL/kg ethanol or distilled water. One hour after the ethanol treatment, the gastric mucus content was determined (N=8). *p< 0.05, †p<0.01 compared with the untreated control, and ‡p<0.05 compared with the ethanol-treated control. (C) One hour after the indicated doses of GRE were administered to rats, the gastric mucosal NP-SH concentration was determined (N=8). *p<0.05 compared with the control (zero) group. |
![]() | FIG. 3Dose-dependent effects of BTE on the gastroprotective activities of GRE and GREP as measured in the ethanol-induced ulcer model. Glutinous rice extract (GRE, 30 mg/kg) or its particulate fraction GREP (10 mg/kg) was administered to rats with 0-8 mg/kg black tea extract (BTE) as indicated 30 min before ethanol treatment. *p<0.05, †p<0.01 compared with the distilled water control, ‡p<0.05 compared with the GRE alone group, and §p<0.05 compared with the GREP alone group (N=8). |
![]() | FIG. 4Effects of the albumin, globulin, glutelin, and prolamin fractions isolated from glutinous rice flour on the gastric lesion formation induced by ethanol in rats. (A) The albumin (Alb), globulin (Glo), glutelin (Glu), and prolamin (Pro) fractions suspended in distilled water (DW) were administered to rats in a dose of 10 mg/kg with 8 mg/kg black tea extract 30 min before ethanol treatment. (B) The indicated doses of prolamin fraction were administered to rats with 8 mg/kg black tea extract 30 min before ethanol treatment. Each column represents the mean±SE (N=8). *p<0.05, †p<0.01 compared with the control. |
TABLE 1

TABLE 2

Glutinous rice extract (GRE, 30 mg/kg) or its particulate fraction GREP (10 mg/kg) was administered to rats with or without 8 mg/kg green tea (GTE) and black tea (BTE) extracts 30 min before ethanol treatment. *p<0.05, †p<0.01 compared with the control, ‡p<0.05 compared with the GRE group, and §p<0.05 compared with the GREP group (N=8).
TABLE 3

TABLE 4

The particulate fraction of glutinous rice extract (GREP) was undergone various physical and chemical treatments to inactivate proteins or to remove different groups of proteins as follows: aGREP (3 mg/mL) was incubated at 80℃ for 3 min. bGREP (3 mg/mL) was incubated with 0.01% pepsin and 1% lactic acid at 37℃ for 1 h and neutralized with 2 N NaOH. c-eSixty milligrams of GREP was suspended in 20 mL 5% NaCl, 1% lactic acid, and 70% ethanol and incubated at room temperature for 4, 1, and 4 h, respectively. GREP was then isolated by centrifugation and resuspended in 20 mL distilled water. After the above treatments, GREP preparations were added with 2 mg/mL black tea extract and administered to rats in a dose of 4 mL/kg 30 min before ethanol treatment. *p<0.05, †p<0.01 compared with the distilled water control, and ‡p<0.05, §p<0.01 compared with the native GREP group (N=8).
ACKNOWLEDGEMENTS
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