Journal List > Korean Circ J > v.34(1) > 1074618

TOOLS
Cha, Waksman, Pichard, Satler, Kent, and Lindsay: Cutting Balloon Angioplasty versus Conventional Balloon Angioplasty for In-Stent Restenosis Treated by Intracoronary Radiation Therapy
Original Article

Custom metadata:

DOI: Invalid

Korean Circulation Journal

Korean Circulation Journal 2004; 34(1): 28-34.

Published online: 31 January 2004

DOI: https://doi.org/10.4070/kcj.2004.34.1.28

Cutting Balloon Angioplasty versus Conventional Balloon Angioplasty for In-Stent Restenosis Treated by Intracoronary Radiation Therapy

Dong Hoon Cha, Ron Waksman, Augusto D. Pichard, Lowell F. Satler, Kenneth M. Kent, Joseph Lindsay

Department of Cardiology, Pundang CHA Hospital, Pochon CHA University, Seongnam, Korea.

Department of Cardiology, Washington Hospital Center, Washington, DC, USA.

chadhmd@hotmail.com

Copyright © 2004 The Korean Society of Circulation

Abstract

BACKGROUND: Cutting Balloon angioplasty (CBA) may be a useful treatment modality for in-stent restenosis (ISR) as it maintains a stable position during dilatation and results in potentially less injury than plain old balloon angioplasty (POBA). The purpose of this study was to compare CBA and POBA with intracoronary radiation therapy (IRT) for in-stent restenosis (ISR).
METHODS: We selected 157 consecutive patients from the WRIST (Washington Radiation for In-stent restenosis Trial) series of gamma radiation trials using both gamma and beta emitters for ISR of native coronaries or saphenous vein grafts, who were treated with CBA or POBA as the only treatment strategy before intracoronary radiation therapy. Patients in the CBA (N=64) and POBA (N=93) groups were matched for baseline demographic and procedural characteristics. Radiation was delivered successfully in all cases.
RESULTS: At angiographic follow up, acute gain was higher in the CBA group than the POBA group (1.7±.7 mm vs. 1.4±.9 mm, p=0.03). The angiographic restenosis rate (17.1% vs. 23.5%, p=NS) and edge restenosis rate (6.3% vs. 12.2%, p=NS) were not significantly lower in the cutting balloon cohort. At a 6 month clinical follow up, the CBA group showed a statistically decreased rate of clinically driven target vessel revascularization compared to the POBA group (5.7% vs.18.3%, p=0.038).
CONCLUSION: Cutting balloon angioplasty is a reasonable treatment strategy for in-stent restenosis prior to intracoronary radiation therapy.

Keywords: Cutting balloon, Brachytherapy, Coronary restenosis, Stents

TOOLS
Similar articles