Coronary artery spasm plays an important role in the pathogenesis of variant angina and the incidence during routine coronary angiography has been reported 0.26 to 2.9 percent. Most of these cases are induced by the provocation with ergonovine or acetylcholine, and mechanical irritation of coronary artery by catheter, but spontaneous alternative spasm associated with occlusion in the left anterior descending and circumflex arteries is very rare. We report a fifty three year-old male patient presenting as a variant angina due to alternativee spontaneous occlusive spasmin left anterior descending and left circumflex arteries during diagnostic coronary angiogram. The spasm was relieved spontaneously or by the administration of intracoronary nitroglycerin. No chest pain was documented after medication with calcium-channel blocker and nitrates on 6-month clinical follow-up.