Journal List > Korean Circ J > v.18(4) > 1072446

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Seo, Kim, Park, Ryu, Kim, Oh, Park, Cho, Choi, and Lee: The Role of Pulmonary Circulation in the Metabolism of Atrial Natriuretic Factor in Man
Original Article
Korean Circulation Journal

Korean Circulation Journal 1988; 18(4): 553-558.

Published online: 31 December 1988

DOI: https://doi.org/10.4070/kcj.1988.18.4.553

The Role of Pulmonary Circulation in the Metabolism of Atrial Natriuretic Factor in Man

Jung Don Seo, M.D., Hyo Soo Kim, M.D., Seong Wook Park, M.D., Kyu Hyung Ryu, M.D., Cheol Ho Kim, M.D., Byung Hee Oh, M.D., Young Bae Park, M.D., Bo Yeon Cho, M.D., Yun Shik Choi, M.D., Young Woo Lee, M.D.

Copyright © 1988 The Korean Society of Circulation

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

To evaluate the role pulmonary capillary in the metabolism of atrial natriuretic factor(ANF), we measured plasma level of immunoreative(IR) ANF in pulmonary artery, pulmonary vein, left atrium and aorta simultaneously in 7 cardiac patients with patent with foramen ovale without shunt and 8 cardiac patients with atrial septal defect(ASD) with only left to right shunt during cardiac catheterization.
Plasma level of IR-ANF in pulmonary vein was significantly lower to be involved in the metabolism of ANF and that ANF secreted by left atrial myocardium is mainly drained through coronary sinus into right atrial cavity rather than directly into left atrial cavity through thebesian vein.

Keywords: Atrial natriuretic factor, Pulmonary circulation

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