The systolic and diastolic blood pressures of patients were declined significantly at 4th week and at 12th week(p<0.005) without significant change of rate and body weight. These data were also analyzed in terms of the percent of patients with marked, moderate and mild responses. Enalapril yielded a 72.7% response rate in marked fall and 22.7% response rate in moderate fall which revealed 95.4% of good response rate. Enalapril was tolerated and showed no significant clinical and biochemical adverse reactions.

In conclusion, these results indicate that monotherapy with enalapril 10 mg in a single daily dose was effective in the management of mild to moderate uncomplicated essential hypertension and was well tolerated.