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Abstract
The abnormalities of left ventricular ejection patterns have been studied using echocardiography, contrast angiography, radionuclide angiography, and apex cardiography in patients with various heart disease. Recently it has been recognized that diastolic impairment may occur in the absence of abnormal systolic performance in hypertension, valvular heart disease, ischemic heart diseases, and cardiomyopathies.
In order to identify whether diastolic dysfunction can develop without systolic dysfunction, we evaluated patterns of left ventricular filling and ejection by echocardiography in 10 chronic mitral regurgitations without pulmonary congestion symptom, who were confirmed by cardiac catheterization.
Indices of left ventricular systolic function, including ejection fraction, fractional shortening, ejection rate, mean velocity of circumferential fiber shortening, and preejection period/left ventricular ejection time revealed no significant difference in mitral regurgitation patients compared with normal control group.
Diastolic parameters, including atrial emptying index,mean velocity of circumferential fiber lengthening, rapid filling period, and rapid filling velocity were changed significantly in mitral regurgitation.
There were no significant alterations in blood pressure and heart rate between two groups. It is concluded that impaired diastolic performance may be frequently encountered in patients with chronic mitral regurgitation and intact systolic function.
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