Journal List > Korean Circ J > v.16(2) > 1072270

Lee, Oh, Park, Seo, Lee, Kim, Kim, and Min: A Study of Regional Myocardial Function by Biplane Coronary Cineangiogram

Abstract

The analysis of regional myocardial function is important for the evaluation of myocardial performance. We evaluated whether the motion images of the coronary bifurcation points can be used for computation of the regional deformation and the regional wall stress.
In 5 mongrel dogs, 4 to 7 lead markers were implanted adjacent to the bifurcarion points of coronary artery. Left ventricular pressure curve was obtained, and left ventriculography was performed to measure the major and minor axes of the left ventricle. Afterthen, biplane coronary arteriography was performed.
The motion images of the lead markers and the corresponding coronary bifurcation points were used as landmarkers for the kinetic analysis of the regional wall deformation and wall stress. The results of the analysis using two kinds of landmarkers were well correlated(P<0.001).
Analysis of the diagnosis biplane coronary cineangiograms of each patient group demonstrated that quite difference wave forms between the normally perfused segment and the underperfused segments.
In group I there was no coronary arterial narrowings and no regional wall motion abnormalities. Their mean and peak wall thicking were 10.10±9.28% and 47.99±20.70%. And their peak and mean values of circumferential and longitudinal wall stresses are as follows; 2.70±0.74×105dyn/cm2, 2.34±0.71×105dyn/cm2, 0.84±0.21×105dyn/cm2, 2.34±0.71×105dyn/cm2, 0.84±0.21×105dyn/cm2 and 0.64±0.13×105dyn/cm2.
Of 5 male patients having coronary arterial disease with regional wall motion abnotmalities(Group III), 2patients have single vessel disease, 2 paitents have 2 vessel disease. In subgroup b of group III, there was a significant decrease of regional wall thickening(mean and peak value; 0.54±9.91%.14.87±12.055; P<0.001 vs. group I), and increasing tendency of regional wall stresses.
Using biplane coronary cineangiogram, which is routine diagnostic procedure in coronary artery disease, this method can valuate regional myocardial function. And this method can evaluate regional myocardial function. And this method will be especially useful, when serial coronary cineangiograms are needed for serial evaluation of patients, such as before and after percutaneous transluminal coronary angioplasty, coronary arterial bypass graft surgery, etc.

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