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Abstract
Objective
The objective of this study was to determine the detection rate of respiratory viruses and investigate the associated factors with respiratory virus detection in newborn infants with suspected infection.
Methods
From January 2013 to December 2015, respiratory virus real-time polymerase chain reaction (RT-PCR) results were obtained from 136 newborn infants aged ≤28 days who admitted to the neonatal intensive care unit (NICU) of Dong-A University Hospital with suspected infectious diseases. We performed a retrospective analysis of the detection rate of respiratory virus, classes of respiratory viruses, clinical characteristics, and social environment characteristics associated with respiratory virus detection.
Results
Of the 136 infants, 36 infants (26.5%) had the 37 following respiratory viruses: Respiratory syncytial virus (n=23), Rhinovirus (n=10), Parainfluenza virus (n=2), Influenza virus (n=1), and Corona virus (n=1). The detection of respiratory viruses was significantly associated with the old age at admission (17.3±5.8 vs. 10.6±6.8 days), the presence of respiratory symptoms: cough (72.2% vs. 7%), rhinorrhea (63.9% vs. 10%), rale (16.7% vs. 1%), a family history of respiratory illness (38.9% vs. 13%), especially siblings’ respiratory illness (33.3% vs. 8%), and a seasonal preference (October-March) (80.6% vs. 50%) (P<0.01).
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Fig. 1
Respiratory virus detection classes. RT-PCR, real-time polymerase chain reaction; RSV, respiratory syncytial virus.
Fig. 2
Monthly distribution of respiratory virus detection cases. PCR, polymerase chain reaction; RSV, respiratory syncytial virus.
Table 1.
Clinical Characteristics Related with Respiratory Virus Detection
Table 2.
Socio-Environment Characteristics Related to Respiratory Virus Detection
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