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Kwon, Kim, Choi, Park, Jo, Lee, and Ko: Primary Urethral Adenocarcinoma in a Young Man Who Presented with Voiding Dysfunction
Case Report
Korean Journal of Urology

Korean Journal of Urology 2006; 47(7): 802-805.

Published online: 31 July 2006

DOI: https://doi.org/10.4111/kju.2006.47.7.802

Primary Urethral Adenocarcinoma in a Young Man Who Presented with Voiding Dysfunction

Nam Sung Kwon, Geon Hun Kim, Han Yung Choi, Kwanjin Park, Moon Ki Jo, Chong Wook Lee, Jae Soo Ko1

Department of Urology, Korea Cancer Center Hospital, Seoul, Korea.

1Department of Pathology, Korea Cancer Center Hospital, Seoul, Korea.

Corresponding author (urodori@yahoo.co.kr)

Received 3 March 2006       Accepted 13 April 2006

Copyright © 2006 The Korean Urological Association

Abstract

Primary urethral carcinoma accounts for less than 1% of the malignancies in males and adenocarcinoma accounts for 5% of all urethral carcinomas. A 36-year-old man with a history suggestive of urethral stricture was scheduled to undergo retrograde urethrography and visual urethrotomy. On urethroscopic examination, an abnormal polypoid mass was found in the proximal bulbous urethra, so transurethral resection biopsy was added to the urethrotomy. Histopathologic examination demonstrated urethral adenocarcinoma with no invasion to the corpus spongiosum and cavernosa on the magnetic resonance imaging. There was no evidence of metastasis and the search for the primary focus of adenocarcinoma revealed that the tumor originated from the urethra. The patient underwent segmental urethral resection and there has been no recurrence for 1-year follow-up.

Keywords: Adenocarcinoma, Male, Urethra

Figures and Tables

Fig. 1
Retrograde urethrography shows distal bulbous urethral narrowing and an indefinite filling defect at the proximal bulbous urethra.
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Fig. 2
Urethroscopic findings of the proximal bulbous urethra reveals 0.5-1cm sized multiple polypoid masses.
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Fig. 3
Microscopic findings of the urethral masses. There is complex glandular pattern with hemorrhage, pleomorphic nuclear shape and mitoses, and these are typical of adenocarcinoma (H&E, ×400).
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Fig. 4
Histologic findings of the segmental urethrectomy. There is focal residual adenocarcinoma at the subepithelium (H&E, ×100).
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